Effect of seasonal variation on adult clinical laboratory parameters in Rwanda, Zambia, and Uganda: implications for HIV biomedical prevention trials

To investigate the effect of seasonal variation on adult clinical laboratory parameters in Rwanda, Zambia, and Uganda and determine its implications for HIV prevention and other clinical trials. Volunteers in a cross-sectional study to establish laboratory reference intervals were asked to return fo...

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Veröffentlicht in:	PloS one 2014-08, Vol.9 (8), p.e105089-e105089
Hauptverfasser:	Ruzagira, Eugene, Abaasa, Andrew, Karita, Etienne, Mulenga, Joseph, Kilembe, William, Allen, Susan, Bahemuka, Ubaldo, Bwanika, Agnes N, Levin, Jonathan, Price, Matthew A, Kamali, Anatoli
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome Adolescent Adult AIDS Alanine Alanine transaminase Alkaline phosphatase Aspartate Aspartate aminotransferase Bilirubin Biology and Life Sciences Biomedical laboratories Blood Blood & organ donations Blood cells CD4 antigen CD8 antigen Climate Clinical trials Councils Creatine Creatine kinase Creatinine Cross-Sectional Studies Dry season Eosinophils Epidemiology Erythrocytes Ethics Family medical history Female Health aspects Health care Hematocrit Hematologic Tests Hemoglobin Hemoglobins Hepatitis Hepatitis B HIV HIV - isolation & purification HIV Infections - blood HIV Infections - diagnosis HIV Infections - epidemiology HIV Infections - prevention & control Human immunodeficiency virus Humans Intervals L-Lactate dehydrogenase Laboratories Lactate dehydrogenase Lactic acid Leukocytes Leukocytes (basophilic) Leukocytes (eosinophilic) Leukocytes (neutrophilic) Lymphocytes Lymphocytes T Malaria Male Medical research Medicine and Health Sciences Middle Aged Monocytes Muscular dystrophy Parameter estimation Parameters Platelets Population Pregnant women Prevention Public health Rainy season Reference Values Research and Analysis Methods Rwanda - epidemiology Seasonal variability Seasonal variations Seasons Sexually transmitted diseases STD Syphilis T cells Uganda - epidemiology Volunteers Womens health Young Adult Zambia - epidemiology
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