Neural substrate of initiation of cross-modal working memory retrieval
Cross-modal working memory requires integrating stimuli from different modalities and it is associated with co-activation of distributed networks in the brain. However, how brain initiates cross-modal working memory retrieval remains not clear yet. In the present study, we developed a cued matching...
Gespeichert in:
| Veröffentlicht in: | PloS one 2014-08, Vol.9 (8), p.e103991-e103991 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e103991 |
|---|---|
| container_issue | 8 |
| container_start_page | e103991 |
| container_title | PloS one |
| container_volume | 9 |
| creator | Zhang, Yangyang Hu, Yang Guan, Shuchen Hong, Xiaolong Wang, Zhaoxin Li, Xianchun |
| description | Cross-modal working memory requires integrating stimuli from different modalities and it is associated with co-activation of distributed networks in the brain. However, how brain initiates cross-modal working memory retrieval remains not clear yet. In the present study, we developed a cued matching task, in which the necessity for cross-modal/unimodal memory retrieval and its initiation time were controlled by a task cue appeared in the delay period. Using functional magnetic resonance imaging (fMRI), significantly larger brain activations were observed in the left lateral prefrontal cortex (l-LPFC), left superior parietal lobe (l-SPL), and thalamus in the cued cross-modal matching trials (CCMT) compared to those in the cued unimodal matching trials (CUMT). However, no significant differences in the brain activations prior to task cue were observed for sensory stimulation in the l-LPFC and l-SPL areas. Although thalamus displayed differential responses to the sensory stimulation between two conditions, the differential responses were not the same with responses to the task cues. These results revealed that the frontoparietal-thalamus network participated in the initiation of cross-modal working memory retrieval. Secondly, the l-SPL and thalamus showed differential activations between maintenance and working memory retrieval, which might be associated with the enhanced demand for cognitive resources. |
| doi_str_mv | 10.1371/journal.pone.0103991 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_plos_</sourceid><recordid>TN_cdi_plos_journals_1551148577</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A416975338</galeid><doaj_id>oai_doaj_org_article_40f0d045e6f144269d69dea54b253316</doaj_id><sourcerecordid>A416975338</sourcerecordid><originalsourceid>FETCH-LOGICAL-c692t-2220aa0fb030322ead910c5f084c2f46ca77ab0d3a1ffd84e295aeba707f2c363</originalsourceid><addsrcrecordid>eNqNkl1v0zAUhiMEYmPwDxBUQkJw0eKvJM0N0jQxqDQxia9b68Q5bl2cuNjOYP8eZ82mBu0C2ZK_nvMe-_jNsueULCgv6but630HdrFzHS4IJbyq6IPsmFaczQtG-MOD-VH2JIQtITlfFsXj7IjlpCKMk-Ps_DP2Huws9HWIHiLOnJ6ZzkQD0bhuWCnvQpi3rknYb-d_mm49a7F1_nrmMXqDV2CfZo802IDPxvEk-37-4dvZp_nF5cfV2enFXBUVi3PGGAEguiaccMYQmooSlWuyFIppUSgoS6hJw4Fq3SwFsioHrKEkpWaKF_wke7nX3VkX5FiCIGmeUyqWeVkmYrUnGgdbufOmBX8tHRh5s-H8WoKPRlmUgmjSEJFjoakQrKia1BFyUbOcczpkez9m6-sWG4VdKpGdiE5POrORa3clBWWUcZEE3owC3v3qMUTZmqDQWujQ9ft7FyT90pDr1T_o_a8bqTWkB5hOu5RXDaLyVNCiKtPFl4la3EOl1mBrVPKLNml_EvB2EpCYiH_iGvoQ5Orrl_9nL39M2dcH7AbBxk1wth-sFaag2IM3ZvOo74pMiRzsflsNOdhdjnZPYS8OP-gu6Nbf_C9Vd_me</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1551148577</pqid></control><display><type>article</type><title>Neural substrate of initiation of cross-modal working memory retrieval</title><source>MEDLINE</source><source>Full-Text Journals in Chemistry (Open access)</source><source>DOAJ Directory of Open Access Journals</source><source>Public Library of Science (PLoS)(OpenAccess)</source><source>PubMed Central</source><source>EZB Electronic Journals Library</source><creator>Zhang, Yangyang ; Hu, Yang ; Guan, Shuchen ; Hong, Xiaolong ; Wang, Zhaoxin ; Li, Xianchun</creator><contributor>Antal, Andrea</contributor><creatorcontrib>Zhang, Yangyang ; Hu, Yang ; Guan, Shuchen ; Hong, Xiaolong ; Wang, Zhaoxin ; Li, Xianchun ; Antal, Andrea</creatorcontrib><description>Cross-modal working memory requires integrating stimuli from different modalities and it is associated with co-activation of distributed networks in the brain. However, how brain initiates cross-modal working memory retrieval remains not clear yet. In the present study, we developed a cued matching task, in which the necessity for cross-modal/unimodal memory retrieval and its initiation time were controlled by a task cue appeared in the delay period. Using functional magnetic resonance imaging (fMRI), significantly larger brain activations were observed in the left lateral prefrontal cortex (l-LPFC), left superior parietal lobe (l-SPL), and thalamus in the cued cross-modal matching trials (CCMT) compared to those in the cued unimodal matching trials (CUMT). However, no significant differences in the brain activations prior to task cue were observed for sensory stimulation in the l-LPFC and l-SPL areas. Although thalamus displayed differential responses to the sensory stimulation between two conditions, the differential responses were not the same with responses to the task cues. These results revealed that the frontoparietal-thalamus network participated in the initiation of cross-modal working memory retrieval. Secondly, the l-SPL and thalamus showed differential activations between maintenance and working memory retrieval, which might be associated with the enhanced demand for cognitive resources.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0103991</identifier><identifier>PMID: 25090230</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Acoustic Stimulation ; Adult ; Biology and Life Sciences ; Brain ; Brain Mapping ; Cognitive ability ; Color ; Computer networks ; Cortex (parietal) ; Cortex (somatosensory) ; Cross-modal ; Cues ; Female ; Functional magnetic resonance imaging ; Humans ; Magnetic resonance ; Magnetic Resonance Imaging ; Male ; Matching ; Memory ; Memory, Short-Term - physiology ; Neural networks ; Neuroimaging ; Neurosciences ; NMR ; Nuclear magnetic resonance ; Parietal lobe ; Parietal Lobe - anatomy & histology ; Parietal Lobe - physiology ; Pattern Recognition, Physiological - physiology ; Pattern Recognition, Visual - physiology ; Photic Stimulation ; Prefrontal cortex ; Prefrontal Cortex - anatomy & histology ; Prefrontal Cortex - physiology ; Retrieval ; Sensory stimulation ; Short term memory ; Somatosensory cortex ; Substrates ; Task Performance and Analysis ; Thalamus ; Thalamus - anatomy & histology ; Thalamus - physiology ; Visual task performance</subject><ispartof>PloS one, 2014-08, Vol.9 (8), p.e103991-e103991</ispartof><rights>COPYRIGHT 2014 Public Library of Science</rights><rights>2014 Zhang et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2014 Zhang et al 2014 Zhang et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c692t-2220aa0fb030322ead910c5f084c2f46ca77ab0d3a1ffd84e295aeba707f2c363</citedby><cites>FETCH-LOGICAL-c692t-2220aa0fb030322ead910c5f084c2f46ca77ab0d3a1ffd84e295aeba707f2c363</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121234/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121234/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,2102,2928,23866,27924,27925,53791,53793,79600,79601</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25090230$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Antal, Andrea</contributor><creatorcontrib>Zhang, Yangyang</creatorcontrib><creatorcontrib>Hu, Yang</creatorcontrib><creatorcontrib>Guan, Shuchen</creatorcontrib><creatorcontrib>Hong, Xiaolong</creatorcontrib><creatorcontrib>Wang, Zhaoxin</creatorcontrib><creatorcontrib>Li, Xianchun</creatorcontrib><title>Neural substrate of initiation of cross-modal working memory retrieval</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>Cross-modal working memory requires integrating stimuli from different modalities and it is associated with co-activation of distributed networks in the brain. However, how brain initiates cross-modal working memory retrieval remains not clear yet. In the present study, we developed a cued matching task, in which the necessity for cross-modal/unimodal memory retrieval and its initiation time were controlled by a task cue appeared in the delay period. Using functional magnetic resonance imaging (fMRI), significantly larger brain activations were observed in the left lateral prefrontal cortex (l-LPFC), left superior parietal lobe (l-SPL), and thalamus in the cued cross-modal matching trials (CCMT) compared to those in the cued unimodal matching trials (CUMT). However, no significant differences in the brain activations prior to task cue were observed for sensory stimulation in the l-LPFC and l-SPL areas. Although thalamus displayed differential responses to the sensory stimulation between two conditions, the differential responses were not the same with responses to the task cues. These results revealed that the frontoparietal-thalamus network participated in the initiation of cross-modal working memory retrieval. Secondly, the l-SPL and thalamus showed differential activations between maintenance and working memory retrieval, which might be associated with the enhanced demand for cognitive resources.</description><subject>Acoustic Stimulation</subject><subject>Adult</subject><subject>Biology and Life Sciences</subject><subject>Brain</subject><subject>Brain Mapping</subject><subject>Cognitive ability</subject><subject>Color</subject><subject>Computer networks</subject><subject>Cortex (parietal)</subject><subject>Cortex (somatosensory)</subject><subject>Cross-modal</subject><subject>Cues</subject><subject>Female</subject><subject>Functional magnetic resonance imaging</subject><subject>Humans</subject><subject>Magnetic resonance</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Matching</subject><subject>Memory</subject><subject>Memory, Short-Term - physiology</subject><subject>Neural networks</subject><subject>Neuroimaging</subject><subject>Neurosciences</subject><subject>NMR</subject><subject>Nuclear magnetic resonance</subject><subject>Parietal lobe</subject><subject>Parietal Lobe - anatomy & histology</subject><subject>Parietal Lobe - physiology</subject><subject>Pattern Recognition, Physiological - physiology</subject><subject>Pattern Recognition, Visual - physiology</subject><subject>Photic Stimulation</subject><subject>Prefrontal cortex</subject><subject>Prefrontal Cortex - anatomy & histology</subject><subject>Prefrontal Cortex - physiology</subject><subject>Retrieval</subject><subject>Sensory stimulation</subject><subject>Short term memory</subject><subject>Somatosensory cortex</subject><subject>Substrates</subject><subject>Task Performance and Analysis</subject><subject>Thalamus</subject><subject>Thalamus - anatomy & histology</subject><subject>Thalamus - physiology</subject><subject>Visual task performance</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>DOA</sourceid><recordid>eNqNkl1v0zAUhiMEYmPwDxBUQkJw0eKvJM0N0jQxqDQxia9b68Q5bl2cuNjOYP8eZ82mBu0C2ZK_nvMe-_jNsueULCgv6but630HdrFzHS4IJbyq6IPsmFaczQtG-MOD-VH2JIQtITlfFsXj7IjlpCKMk-Ps_DP2Huws9HWIHiLOnJ6ZzkQD0bhuWCnvQpi3rknYb-d_mm49a7F1_nrmMXqDV2CfZo802IDPxvEk-37-4dvZp_nF5cfV2enFXBUVi3PGGAEguiaccMYQmooSlWuyFIppUSgoS6hJw4Fq3SwFsioHrKEkpWaKF_wke7nX3VkX5FiCIGmeUyqWeVkmYrUnGgdbufOmBX8tHRh5s-H8WoKPRlmUgmjSEJFjoakQrKia1BFyUbOcczpkez9m6-sWG4VdKpGdiE5POrORa3clBWWUcZEE3owC3v3qMUTZmqDQWujQ9ft7FyT90pDr1T_o_a8bqTWkB5hOu5RXDaLyVNCiKtPFl4la3EOl1mBrVPKLNml_EvB2EpCYiH_iGvoQ5Orrl_9nL39M2dcH7AbBxk1wth-sFaag2IM3ZvOo74pMiRzsflsNOdhdjnZPYS8OP-gu6Nbf_C9Vd_me</recordid><startdate>20140804</startdate><enddate>20140804</enddate><creator>Zhang, Yangyang</creator><creator>Hu, Yang</creator><creator>Guan, Shuchen</creator><creator>Hong, Xiaolong</creator><creator>Wang, Zhaoxin</creator><creator>Li, Xianchun</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20140804</creationdate><title>Neural substrate of initiation of cross-modal working memory retrieval</title><author>Zhang, Yangyang ; Hu, Yang ; Guan, Shuchen ; Hong, Xiaolong ; Wang, Zhaoxin ; Li, Xianchun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c692t-2220aa0fb030322ead910c5f084c2f46ca77ab0d3a1ffd84e295aeba707f2c363</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Acoustic Stimulation</topic><topic>Adult</topic><topic>Biology and Life Sciences</topic><topic>Brain</topic><topic>Brain Mapping</topic><topic>Cognitive ability</topic><topic>Color</topic><topic>Computer networks</topic><topic>Cortex (parietal)</topic><topic>Cortex (somatosensory)</topic><topic>Cross-modal</topic><topic>Cues</topic><topic>Female</topic><topic>Functional magnetic resonance imaging</topic><topic>Humans</topic><topic>Magnetic resonance</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Matching</topic><topic>Memory</topic><topic>Memory, Short-Term - physiology</topic><topic>Neural networks</topic><topic>Neuroimaging</topic><topic>Neurosciences</topic><topic>NMR</topic><topic>Nuclear magnetic resonance</topic><topic>Parietal lobe</topic><topic>Parietal Lobe - anatomy & histology</topic><topic>Parietal Lobe - physiology</topic><topic>Pattern Recognition, Physiological - physiology</topic><topic>Pattern Recognition, Visual - physiology</topic><topic>Photic Stimulation</topic><topic>Prefrontal cortex</topic><topic>Prefrontal Cortex - anatomy & histology</topic><topic>Prefrontal Cortex - physiology</topic><topic>Retrieval</topic><topic>Sensory stimulation</topic><topic>Short term memory</topic><topic>Somatosensory cortex</topic><topic>Substrates</topic><topic>Task Performance and Analysis</topic><topic>Thalamus</topic><topic>Thalamus - anatomy & histology</topic><topic>Thalamus - physiology</topic><topic>Visual task performance</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zhang, Yangyang</creatorcontrib><creatorcontrib>Hu, Yang</creatorcontrib><creatorcontrib>Guan, Shuchen</creatorcontrib><creatorcontrib>Hong, Xiaolong</creatorcontrib><creatorcontrib>Wang, Zhaoxin</creatorcontrib><creatorcontrib>Li, Xianchun</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>ProQuest Nursing and Allied Health Journals</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>ProQuest_Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database (Proquest)</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection (Proquest) (PQ_SDU_P3)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>https://resources.nclive.org/materials</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Agriculture Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest advanced technologies & aerospace journals</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Materials science collection</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Engineering collection</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhang, Yangyang</au><au>Hu, Yang</au><au>Guan, Shuchen</au><au>Hong, Xiaolong</au><au>Wang, Zhaoxin</au><au>Li, Xianchun</au><au>Antal, Andrea</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Neural substrate of initiation of cross-modal working memory retrieval</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2014-08-04</date><risdate>2014</risdate><volume>9</volume><issue>8</issue><spage>e103991</spage><epage>e103991</epage><pages>e103991-e103991</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>Cross-modal working memory requires integrating stimuli from different modalities and it is associated with co-activation of distributed networks in the brain. However, how brain initiates cross-modal working memory retrieval remains not clear yet. In the present study, we developed a cued matching task, in which the necessity for cross-modal/unimodal memory retrieval and its initiation time were controlled by a task cue appeared in the delay period. Using functional magnetic resonance imaging (fMRI), significantly larger brain activations were observed in the left lateral prefrontal cortex (l-LPFC), left superior parietal lobe (l-SPL), and thalamus in the cued cross-modal matching trials (CCMT) compared to those in the cued unimodal matching trials (CUMT). However, no significant differences in the brain activations prior to task cue were observed for sensory stimulation in the l-LPFC and l-SPL areas. Although thalamus displayed differential responses to the sensory stimulation between two conditions, the differential responses were not the same with responses to the task cues. These results revealed that the frontoparietal-thalamus network participated in the initiation of cross-modal working memory retrieval. Secondly, the l-SPL and thalamus showed differential activations between maintenance and working memory retrieval, which might be associated with the enhanced demand for cognitive resources.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>25090230</pmid><doi>10.1371/journal.pone.0103991</doi><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1932-6203 |
| ispartof | PloS one, 2014-08, Vol.9 (8), p.e103991-e103991 |
| issn | 1932-6203 1932-6203 |
| language | eng |
| recordid | cdi_plos_journals_1551148577 |
| source | MEDLINE; Full-Text Journals in Chemistry (Open access); DOAJ Directory of Open Access Journals; Public Library of Science (PLoS)(OpenAccess); PubMed Central; EZB Electronic Journals Library |
| subjects | Acoustic Stimulation Adult Biology and Life Sciences Brain Brain Mapping Cognitive ability Color Computer networks Cortex (parietal) Cortex (somatosensory) Cross-modal Cues Female Functional magnetic resonance imaging Humans Magnetic resonance Magnetic Resonance Imaging Male Matching Memory Memory, Short-Term - physiology Neural networks Neuroimaging Neurosciences NMR Nuclear magnetic resonance Parietal lobe Parietal Lobe - anatomy & histology Parietal Lobe - physiology Pattern Recognition, Physiological - physiology Pattern Recognition, Visual - physiology Photic Stimulation Prefrontal cortex Prefrontal Cortex - anatomy & histology Prefrontal Cortex - physiology Retrieval Sensory stimulation Short term memory Somatosensory cortex Substrates Task Performance and Analysis Thalamus Thalamus - anatomy & histology Thalamus - physiology Visual task performance |
| title | Neural substrate of initiation of cross-modal working memory retrieval |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-01T09%3A58%3A12IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Neural%20substrate%20of%20initiation%20of%20cross-modal%20working%20memory%20retrieval&rft.jtitle=PloS%20one&rft.au=Zhang,%20Yangyang&rft.date=2014-08-04&rft.volume=9&rft.issue=8&rft.spage=e103991&rft.epage=e103991&rft.pages=e103991-e103991&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0103991&rft_dat=%3Cgale_plos_%3EA416975338%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1551148577&rft_id=info:pmid/25090230&rft_galeid=A416975338&rft_doaj_id=oai_doaj_org_article_40f0d045e6f144269d69dea54b253316&rfr_iscdi=true |