Cascade bioassay evidence for the existence of urothelium-derived inhibitory factor in Guinea pig urinary bladder

Our aim was to investigate whether guinea pig urothelium-derived bioactivities compatible with the existence of urothelium-derived inhibitory factor could be demonstrated by in vitro serial bioassay and whether purinergic P1 receptor agonists, nitric oxide, nitrite or prostaglandins might explain ob...

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Veröffentlicht in:	PloS one 2014-08, Vol.9 (8), p.e103932
Hauptverfasser:	Guan, Na N, Thor, Anna, Hallén, Katarina, Wiklund, N Peter, Gustafsson, Lars E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Analysis Animals Arginine Bioassay Bioassays Biological Assay - methods Biological assays Biology and Life Sciences Bladder Carbachol Carbachol - pharmacology Contraction COX-2 inhibitors Diclofenac Diclofenac - pharmacology Experiments Guinea Pigs Inhibitors Medicin och hälsovetenskap Medicine and Health Sciences Motility NG-Nitroarginine methyl ester NG-Nitroarginine Methyl Ester - pharmacology Nitric oxide Nitric-oxide synthase Nitrites Oxygenase Pharmacology Physiology Prostaglandin endoperoxide synthase Prostaglandins Research and Analysis Methods Rhythms Scopolamine Scopolamine - pharmacology Smooth muscle Surgery Theophylline Tissues Ureter Urinary bladder Urinary Bladder - drug effects Urinary Bladder - metabolism Urogenital system Urology Urothelium Urothelium - drug effects Urothelium - metabolism
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