Serum autotaxin is a parameter for the severity of liver cirrhosis and overall survival in patients with liver cirrhosis--a prospective cohort study

Autotaxin (ATX) and its product lysophosphatidic acid (LPA) are considered to be involved in the development of liver fibrosis and elevated levels of serum ATX have been found in patients with hepatitis C virus associated liver fibrosis. However, the clinical role of systemic ATX in the stages of li...

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Veröffentlicht in:	PloS one 2014-07, Vol.9 (7), p.e103532-e103532
Hauptverfasser:	Pleli, Thomas, Martin, Daniel, Kronenberger, Bernd, Brunner, Friederike, Köberle, Verena, Grammatikos, Georgios, Farnik, Harald, Martinez, Yolanda, Finkelmeier, Fabian, Labocha, Sandra, Ferreirós, Nerea, Zeuzem, Stefan, Piiper, Albrecht, Waidmann, Oliver
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Adult Aged Biomarkers - blood Chromatography Chronic illnesses Cirrhosis Cohort analysis Complications Confidence intervals Encephalopathy Enzyme-linked immunosorbent assay Enzymes Esophagus Female Fibrosis Hepatic encephalopathy Hepatitis Hepatitis C Hepatitis C virus Humans Hypertension Immunoassay Laboratories Liquid chromatography Liver Liver cancer Liver cirrhosis Liver Cirrhosis - blood Liver diseases Liver transplantation Liver transplants Lymphoma Lymphomas Lysophosphatidic acid Male Mass spectrometry Mass spectroscopy Medical prognosis Medical research Medicine and Health Sciences Middle Aged NMR Nuclear magnetic resonance Pancreatic cancer Parameters Patient outcomes Patients Phosphoric Diester Hydrolases - blood Prognosis Prospective Studies Regression analysis Rodents Scientific imaging Serum levels Statistical analysis Survival Survival Analysis Transplantation Viruses
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