Functional effect of polymorphisms in the promoter of TNFAIP3 (A20) in acute pancreatitis in the Han Chinese population

The zinc finger protein A20 is an important negative regulator of inflammation; polymorphisms in the corresponding gene, TNFAIP3, have been reported to be associated with several inflammation diseases. However, only a few studies have focused on the relationship between TNFAIP3 polymorphisms and acu...

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Veröffentlicht in:	PloS one 2014-07, Vol.9 (7), p.e103104-e103104
Hauptverfasser:	Liu, Yugang, Dan, Gang, Wu, Lijuan, Chen, Guangyu, Wu, Ailin, Zeng, Ping, Xu, Wanqing
Format:	Artikel
Sprache:	eng
Schlagworte:	A20 protein Abdomen Acute Disease Adult Alleles Arthritis Biology and Life Sciences Cardiovascular disease China - epidemiology Deoxyribonucleic acid Diabetes DNA DNA sequencing DNA-Binding Proteins - genetics Female Gastroenterology Gene expression Gene sequencing Genetic aspects Hospitals Humans IL-1β Inflammation Inflammatory response Interleukin-1beta - immunology Intracellular Signaling Peptides and Proteins - genetics Laboratories Leukocytes Lipopolysaccharides Lupus Male Medicine Middle Aged NF-kappa B - immunology NF-κB protein Nuclear Proteins - genetics Pancreas Pancreatitis Pancreatitis - epidemiology Pancreatitis - genetics Pancreatitis - immunology Pathogenesis Patients Polymorphism Polymorphism, Single Nucleotide Population Promoter Regions, Genetic Rodents Single nucleotide polymorphisms Single-nucleotide polymorphism Stimulation Systemic inflammatory response syndrome Transcription Transcription factors Tumor necrosis factor Tumor Necrosis Factor alpha-Induced Protein 3 Tumor Necrosis Factor-alpha - immunology Tumor necrosis factor-α Zinc Zinc finger proteins
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