Proteomic analysis of Mecistocirrus digitatus and Haemonchus contortus intestinal protein extracts and subsequent efficacy testing in a vaccine trial

Gastrointestinal nematode infections, such as Haemonchus contortus and Mecistocirrus digitatus, are ranked in the top twenty diseases affecting small-holder farmers' livestock, yet research into M. digitatus, which infects cattle and buffalo in Asia is limited. Intestine-derived native protein...

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Veröffentlicht in:	PLoS neglected tropical diseases 2014-06, Vol.8 (6), p.e2909-e2909
Hauptverfasser:	Dicker, Alison J, Inglis, Neil F, Manson, Erin D T, Subhadra, Subhra, Illangopathy, Manikkavasagan, Muthusamy, Raman, Knox, David P
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Antigens Antigens, Helminth - analysis Antigens, Helminth - immunology Antigens, Helminth - isolation & purification Biology and Life Sciences Cattle Cross Protection Farmers Food supply Gastrointestinal Tract - chemistry Health aspects Infections Keratin Livestock Magnetic resonance imaging Nematoda Parasite Load Parasites Protein folding Proteome - analysis Proteome - isolation & purification Proteomics Sheep Sheep Diseases - immunology Sheep Diseases - parasitology Sheep Diseases - prevention & control Studies Trichostrongyloidea - chemistry Trichostrongyloidiasis - immunology Trichostrongyloidiasis - parasitology Trichostrongyloidiasis - prevention & control Trichostrongyloidiasis - veterinary Vaccines Vaccines - administration & dosage Vaccines - immunology
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