A rapid lateral flow immunoassay for the detection of tyrosine phosphatase-like protein IA-2 autoantibodies in human serum

Type 1 diabetes (T1D) results from the destruction of pancreatic insulin-producing beta cells and is strongly associated with the presence of islet autoantibodies. Autoantibodies to tyrosine phosphatase-like protein IA-2 (IA-2As) are considered to be highly predictive markers of T1D. We developed a...

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Veröffentlicht in:	PloS one 2014-07, Vol.9 (7), p.e103088-e103088
Hauptverfasser:	Kikkas, Ingrid, Mallone, Roberto, Larger, Etienne, Volland, Hervé, Morel, Nathalie
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Antigens Autoantibodies Autoantibodies - blood Autoimmunity Beta cells Biology and Life Sciences Diabetes Diabetes mellitus Diabetes mellitus (insulin dependent) Diabetes Mellitus, Type 1 - blood Diabetes Mellitus, Type 1 - diagnosis Diabetes Mellitus, Type 1 - immunology E coli Enzyme-linked immunosorbent assay Enzymes Female Gold Humans Immunoassay Immunoassay - methods Insulin Male Medicine and Health Sciences Middle Aged Nanoparticles Pancreas Patients Phenols (Class of compounds) Phosphatase Phosphatases Protein-tyrosine-phosphatase Proteins Receptor-Like Protein Tyrosine Phosphatases, Class 8 - immunology Sensitivity and Specificity Streptavidin Type 1 diabetes Tyrosine Young Adult
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