Elevated soluble VEGF receptor sFlt-1 correlates with endothelial injury in IgA nephropathy

Endothelial injury, which may present clinically as hypertension, proteinuria and increased von Willebrand Factor (vWF) level, is a common manifestation in IgA nephropathy (IgAN). However, causal factors for endothelial injury in IgAN are not completely understood. An imbalance of vascular endotheli...

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Veröffentlicht in:	PloS one 2014-07, Vol.9 (7), p.e101779
Hauptverfasser:	Zhai, Ya-Ling, Zhu, Li, Shi, Su-Fang, Liu, Li-Jun, Lv, Ji-Cheng, Zhang, Hong
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biology and Life Sciences Biomarkers - blood Case-Control Studies Comparative analysis Correlation Diabetes Diabetes mellitus Diabetic retinopathy Disease prevention Education Endothelium Endothelium, Vascular - pathology Female Glomerulonephritis, IGA - blood Glomerulonephritis, IGA - physiopathology Glomerulonephritis, IGA - urine Hospitals Humans Hypertension Hypertension - blood IgA nephropathy Immunoglobulin A Injuries Kidney diseases Laboratories Male Medicine Medicine and Health Sciences Nephrology Patients Plasma Pre-eclampsia Preeclampsia Protein-tyrosine kinase Proteinuria Proteinuria - blood Replication Research and Analysis Methods Retinopathy Rodents Tyrosine Vascular endothelial growth factor Vascular Endothelial Growth Factor A - blood Vascular Endothelial Growth Factor Receptor-1 - blood Von Willebrand factor von Willebrand Factor - metabolism Young Adult
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