Confirmation and distribution of tetrodotoxin for the first time in terrestrial invertebrates: two terrestrial flatworm species (Bipalium adventitium and Bipalium kewense)

The potent neurotoxin tetrodotoxin (TTX) is known from a diverse array of taxa, but is unknown in terrestrial invertebrates. Tetrodotoxin is a low molecular weight compound that acts by blocking voltage-gated sodium channels, inducing paralysis. However, the origins and ecological functions of TTX i...

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Veröffentlicht in:	PloS one 2014-06, Vol.9 (6), p.e100718
Hauptverfasser:	Stokes, Amber N, Ducey, Peter K, Neuman-Lee, Lorin, Hanifin, Charles T, French, Susannah S, Pfrender, Michael E, Brodie, 3rd, Edmund D, Brodie, Jr, Edmund D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bioaccumulation Biology Biology and Life Sciences Bipalium adventitium Bipalium kewense Chromatography Chromatography, High Pressure Liquid Drinking water Ecological function Ecology and Environmental Sciences Eggs Enzymes Flatworms Immunoassay Immunoenzyme Techniques Invertebrates Liquid chromatography Low molecular weights Molecular weight Neurotoxins Oligochaeta Organ Size Organ Specificity Paralysis Platyhelminthes Predation Prey Skin Sodium Sodium channels (voltage-gated) Taxa Terrestrial environments Tetrodotoxin Tetrodotoxin - metabolism Toxins Turbellaria - metabolism Worms
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