Effect of broccoli sprouts on nasal response to live attenuated influenza virus in smokers: a randomized, double-blind study

Smokers have increased susceptibility and altered innate host defense responses to influenza virus infection. Broccoli sprouts are a source of the Nrf2 activating agentsulforaphane, and short term ingestion of broccoli sprout homogenates (BSH) has been shown to reduce nasal inflammatory responses to...

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Veröffentlicht in:	PloS one 2014-06, Vol.9 (6), p.e98671
Hauptverfasser:	Noah, Terry L, Zhang, Hongtao, Zhou, Haibo, Glista-Baker, Ellen, Müller, Loretta, Bauer, Rebecca N, Meyer, Megan, Murphy, Paula C, Jones, Shannon, Letang, Blanche, Robinette, Carole, Jaspers, Ilona
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alfalfa Analysis Antioxidants Antioxidants (Nutrients) Asthma Biology Biology and Life Sciences Biopsy Brassica - chemistry Broccoli Clinical trials Cytokines Double-Blind Method Double-blind studies Drug dosages Drug resistance Environmental health Enzymes Epithelium Female Gene Expression Regulation - drug effects Health aspects Health care Heme Oxygenase-1 - genetics Humans Infections Inflammation Influenza Influenza A Virus, H1N1 Subtype - immunology Influenza A Virus, H3N2 Subtype - immunology Influenza Vaccines - immunology Influenza viruses Ingestion Interleukin 6 Male Medicine Medicine and Health Sciences NAD(P)H Dehydrogenase (Quinone) - genetics Nasal Lavage Fluid - immunology Nose - drug effects Nose - immunology Nose - pathology Orthomyxoviridae - immunology Pediatrics Plant Extracts - pharmacology Plant Shoots - chemistry Pollutants Randomization Smokers Smoking Vaccines Vaccines, Attenuated - immunology Vegetables Viruses Young adults Youth smoking
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