Class I ADP-ribosylation factors are involved in enterovirus 71 replication

Enterovirus 71 is one of the major causative agents of hand, foot, and mouth disease in infants and children. Replication of enterovirus 71 depends on host cellular factors. The viral replication complex is formed in novel, cytoplasmic, vesicular compartments. It has not been elucidated which cellul...

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Veröffentlicht in:	PloS one 2014-06, Vol.9 (6), p.e99768
Hauptverfasser:	Wang, Jianmin, Du, Jiang, Jin, Qi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine diphosphate ADP-ribosylation ADP-Ribosylation Factor 1 - genetics ADP-Ribosylation Factor 1 - metabolism ADP-Ribosylation Factors - genetics ADP-Ribosylation Factors - metabolism Antiviral agents Biology Biology and Life Sciences Brefeldin A - pharmacology Cell Line Children Compartments Endoplasmic reticulum Enterovirus Enterovirus A, Human - drug effects Enterovirus A, Human - physiology Enterovirus Infections - genetics Enterovirus Infections - virology Enteroviruses Gene Expression Regulation Gene Knockdown Techniques Genomes Guanidine Guanine Nucleotide Exchange Factors - genetics Guanine Nucleotide Exchange Factors - metabolism Hand-foot-and-mouth disease Host-Pathogen Interactions - genetics Humans Infants Infections Laboratories Membranes Pathogens Pediatric diseases Picornaviridae Protein Binding Proteins Replication Ribonucleic acid Ribosylation RNA siRNA Up-Regulation Viral Proteins - metabolism Virus replication Virus Replication - drug effects Viruses
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