Additive effect between IL-13 polymorphism and cesarean section delivery/prenatal antibiotics use on atopic dermatitis: a birth cohort study (COCOA)

Although cesarean delivery and prenatal exposure to antibiotics are likely to affect the gut microbiome in infancy, their effect on the development of atopic dermatitis (AD) in infancy is unclear. The influence of individual genotypes on these relationships is also unclear. To evaluate with a prospe...

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Veröffentlicht in:	PloS one 2014-05, Vol.9 (5), p.e96603
Hauptverfasser:	Lee, So-Yeon, Yu, Jinho, Ahn, Kang-Mo, Kim, Kyung Won, Shin, Youn Ho, Lee, Kyung-Shin, Hong, Seo Ah, Jung, Young-Ho, Lee, Eun, Yang, Song-I, Seo, Ju-Hee, Kwon, Ji-Won, Kim, Byoung-Ju, Kim, Hyo-Bin, Kim, Woo-Kyung, Song, Dae Jin, Jang, Gwang Cheon, Shim, Jung Yeon, Lee, Soo-Young, Kwon, Ja-Young, Choi, Suk-Joo, Lee, Kyung-Ju, Park, Hee Jin, Won, Hye-Sung, Yoo, Ho-Sung, Kang, Mi-Jin, Kim, Hyung-Young, Hong, Soo-Jong
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Allergic diseases Analysis Anti-Bacterial Agents - adverse effects Anti-Bacterial Agents - therapeutic use Antibiotics Asthma Atopic dermatitis Biology and Life Sciences CD14 antigen Cesarean Section Children Cocoa Cohort analysis Cord blood Cytokines Deoxyribonucleic acid Dermatitis Dermatitis, Atopic - chemically induced Dermatitis, Atopic - genetics DNA Eczema Exposure Female Food allergies Gene polymorphism Gene-Environment Interaction Genetic aspects Genetic Association Studies Genetic Predisposition to Disease Genotypes Gynecology Health risks Hospitals Humans Immune system Infant Infants Interleukin Interleukin 13 Interleukin-13 - genetics Interleukins Intestinal microflora Life sciences Lipopolysaccharide Receptors - genetics Male Medicine Medicine and Health Sciences Microbiomes Microbiota Microbiota (Symbiotic organisms) Obstetrics Pediatrics Physicians Polymorphism Polymorphism, Single Nucleotide Pregnancy Pregnant women Prenatal experience Prenatal exposure Prenatal Exposure Delayed Effects - chemically induced Prenatal Exposure Delayed Effects - genetics Research and Analysis Methods Risk Risk analysis Risk factors Signal transduction Studies Tumor necrosis factor-TNF
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