Normal human pregnancy results in maternal immune activation in the periphery and at the uteroplacental interface

Pregnancy poses a unique challenge to the human immune system: the semi-allogeneic fetus must be protected from maternal immune attack while immunity towards pathogens is maintained. Breakdown in maternal-fetal tolerance can lead to pregnancy-specific diseases with potentially high degrees of morbid...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2014-05, Vol.9 (5), p.e96723-e96723
Hauptverfasser:	Loewendorf, Andrea I, Nguyen, Tina A, Yesayan, Maria N, Kahn, Daniel A
Format:	Artikel
Sprache:	eng
Schlagworte:	Abortion Adult Antigens Biology and Life Sciences Blood Case-Control Studies CD38 antigen CD4 antigen CD8 antigen CD8-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - metabolism Cesarean section Compartments Consortia Cryopreservation Effector cells Female Fetuses Gating Gynecology Health aspects Histocompatibility antigen HLA HLA-DR Antigens - immunology HLA-DR Antigens - metabolism Human subjects Humans Identification Immune system Immunity Immunological memory Immunological tolerance Immunology Immunoregulation Lymphocytes Lymphocytes T Medical treatment Medicine Medicine and Health Sciences Memory cells Miscarriage Morbidity Mortality Obstetrics Peripheral blood Placenta Placenta - immunology Placenta - metabolism Pre-eclampsia Pregnancy Pregnancy - blood Pregnancy - immunology Pregnancy Trimester, Third - physiology Pregnant women Research and Analysis Methods T cell receptors T cells T-Lymphocytes, Regulatory - immunology T-Lymphocytes, Regulatory - metabolism Transcription factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!