A novel highly divergent protein family identified from a viviparous insect by RNA-seq analysis: a potential target for tsetse fly-specific abortifacients

In tsetse flies, nutrients for intrauterine larval development are synthesized by the modified accessory gland (milk gland) and provided in mother's milk during lactation. Interference with at least two milk proteins has been shown to extend larval development and reduce fecundity. The goal of...

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Veröffentlicht in:	PLoS genetics 2014-04, Vol.10 (4), p.e1003874
Hauptverfasser:	Benoit, Joshua B, Attardo, Geoffrey M, Michalkova, Veronika, Krause, Tyler B, Bohova, Jana, Zhang, Qirui, Baumann, Aaron A, Mireji, Paul O, Takáč, Peter, Denlinger, David L, Ribeiro, Jose M, Aksoy, Serap
Format:	Artikel
Sprache:	eng
Schlagworte:	Abortifacient Agents - pharmacology Amino Acid Sequence Amino acids Animals Biology and Life Sciences Breastfeeding & lactation Exons - drug effects Exons - genetics Female Females Fertility - drug effects Fertility - genetics Gene Expression Profiling - methods Gene Knockdown Techniques - methods Genes Genes, Insect - genetics Genetic aspects Genetic research Homeostasis Insect Proteins - genetics Introns - drug effects Introns - genetics Lactation - drug effects Lactation - genetics Lipid Metabolism - drug effects Lipid Metabolism - genetics Male Milk Milk Proteins - genetics Phylogeny Proteins Proteome - genetics Reproduction - drug effects Reproduction - genetics RNA - genetics RNA sequencing Sequence Analysis, RNA - methods Transcriptome - genetics Tsetse Flies - drug effects Tsetse Flies - genetics Tsetse-flies Zoological research
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