Population-based analysis of invasive nontypeable pneumococci reveals that most have defective capsule synthesis genes

Since nasopharyngeal carriage of pneumococcus precedes invasive pneumococcal disease, characteristics of carriage isolates could be incorrectly assumed to reflect those of invasive isolates. While most pneumococci express a capsular polysaccharide, nontypeable pneumococci are sometimes isolated. Car...

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Veröffentlicht in:	PloS one 2014-05, Vol.9 (5), p.e97825-e97825
Hauptverfasser:	Park, In Ho, Geno, K Aaron, Sherwood, Logan K, Nahm, Moon H, Beall, Bernard
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Bacteria Biology and Life Sciences Biosynthetic Pathways - genetics Carrier State - microbiology Defects Disease control Disease prevention Genes Genes, Bacterial Genomics Homology Humans Loci Medicine and Health Sciences Multilocus Sequence Typing Mutation Nose - microbiology Pathology Pneumococcal Infections - microbiology Polysaccharides Polysaccharides, Bacterial - biosynthesis Proteins Respiratory diseases Serotyping Streptococcus infections Streptococcus pneumoniae Streptococcus pneumoniae - genetics Streptococcus pneumoniae - isolation & purification Surveillance Vaccines
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