Effects of acupuncture at GV20 and ST36 on the expression of matrix metalloproteinase 2, aquaporin 4, and aquaporin 9 in rats subjected to cerebral ischemia/reperfusion injury

Ischemic stroke is characterized by high morbidity and mortality worldwide. Matrix metalloproteinase 2 (MMP2), aquaporin (AQP) 4, and AQP9 are linked to permeabilization of the blood-brain barrier (BBB) in cerebral ischemia/reperfusion injury (CIRI). BBB disruption, tissue inflammation, and MMP/AQP...

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Veröffentlicht in:	PloS one 2014-05, Vol.9 (5), p.e97488-e97488
Hauptverfasser:	Xu, Hong, Zhang, Yamin, Sun, Hua, Chen, Suhui, Wang, Fuming
Format:	Artikel
Sprache:	eng
Schlagworte:	Acupuncture Acupuncture Points Acupuncture Therapy - methods Animals Aquaporin 4 Aquaporin 4 - metabolism Aquaporins Aquaporins - metabolism Biology and Life Sciences Blood-brain barrier Blood-Brain Barrier - metabolism Brain - metabolism Brain Edema - metabolism Brain Edema - therapy Brain Ischemia - metabolism Brain Ischemia - therapy Carotid artery Cerebral blood flow Chinese medicine Disease Models, Animal Edema Electroacupuncture - methods Gelatinase A Gene expression Health aspects Infarction, Middle Cerebral Artery - metabolism Infarction, Middle Cerebral Artery - therapy Infiltration Inflammation Inflammation - metabolism Inflammation - therapy Ischemia Kinases Male Matrix metalloproteinase Matrix Metalloproteinase 2 - metabolism Medicine and Health Sciences Metalloproteinase Morbidity mRNA Neuroprotection Occlusion Rats Rats, Sprague-Dawley Reperfusion Reperfusion Injury - metabolism Reperfusion Injury - therapy Research and Analysis Methods RNA Rodents Stomach Stroke
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