Predicting mTOR inhibitors with a classifier using recursive partitioning and Naïve Bayesian approaches

Mammalian target of rapamycin (mTOR) is a central controller of cell growth, proliferation, metabolism, and angiogenesis. Thus, there is a great deal of interest in developing clinical drugs based on mTOR. In this paper, in silico models based on multi-scaffolds were developed to predict mTOR inhibi...

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Veröffentlicht in:PloS one 2014-05, Vol.9 (5), p.e95221-e95221
Hauptverfasser: Wang, Ling, Chen, Lei, Liu, Zhihong, Zheng, Minghao, Gu, Qiong, Xu, Jun
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Sprache:eng
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