Assessment of fetal cell chimerism in transgenic pig lines generated by Sleeping beauty transposition

Human cells migrate between mother and fetus during pregnancy and persist in the respective host for long-term after birth. Fetal microchimerism occurs also in twins sharing a common placenta or chorion. Whether microchimerism occurs in multiparous mammals such as the domestic pig, where fetuses hav...

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Veröffentlicht in:	PloS one 2014-05, Vol.9 (5), p.e96673-e96673
Hauptverfasser:	Garrels, Wiebke, Holler, Stephanie, Taylor, Ulrike, Herrmann, Doris, Niemann, Heiner, Ivics, Zoltan, Kues, Wilfried A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal genetic engineering Animals Animals, Genetically Modified - embryology Animals, Genetically Modified - genetics Biology and Life Sciences Cell migration Cell Movement Cells (Biology) Cellular structure Chimera Chimerism Chorion Cytometry Deoxyribonucleic acid DNA DNA Transposable Elements - genetics Female Fetus - cytology Fetus - metabolism Fetuses Flow cytometry Fluorescence Fluorescence microscopy Genes, Reporter - genetics Genetic engineering Genetically modified animals Genomes Gestation Hogs Laboratory animals Male Microscopy Mothers Offspring Organs Placenta Placenta - physiology Pregnancy Proteins Rodents Semen Semen - metabolism Siblings Sperm Swine Transposition Transposons Twins
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