Shorter men live longer: association of height with longevity and FOXO3 genotype in American men of Japanese ancestry

To determine the relation between height, FOXO3 genotype and age of death in humans. Observational study of 8,003 American men of Japanese ancestry from the Honolulu Heart Program/Honolulu-Asia Aging Study (HHP/HAAS), a genetically and culturally homogeneous cohort followed for over 40 years. A Cox...

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Veröffentlicht in:	PloS one 2014-05, Vol.9 (5), p.e94385-e94385
Hauptverfasser:	He, Qimei, Morris, Brian J, Grove, John S, Petrovitch, Helen, Ross, Webster, Masaki, Kamal H, Rodriguez, Beatriz, Chen, Randi, Donlon, Timothy A, Willcox, D Craig, Willcox, Bradley J
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Aged Aging Analysis Asian Americans - statistics & numerical data Biology and Life Sciences Body Height - genetics Body Height - physiology Cancer Cardiovascular disease Education Fasting Fasting - blood Forkhead Box Protein O3 Forkhead Transcription Factors - genetics FOXO3 protein Gene polymorphism Genetic aspects Genotype Genotype & phenotype Genotypes Geriatrics Health aspects Health care Heart Humans Insulin Insulin - blood Insulin-like growth factor I Insulin-like growth factors Japanese Americans Laboratory testing Life span Longevity Longevity - genetics Longevity - physiology Male Medical research Medicine Medicine and Health Sciences Men Mens health Middle Aged Mortality Polymorphism Polymorphism, Single Nucleotide - genetics Population Proportional Hazards Models Public health Regression analysis Regression coefficients Regression models Risk factors Signaling Single nucleotide polymorphisms Single-nucleotide polymorphism Smoking Studies Veterans
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