Homogenous 96-plex PEA immunoassay exhibiting high sensitivity, specificity, and excellent scalability

Medical research is developing an ever greater need for comprehensive high-quality data generation to realize the promises of personalized health care based on molecular biomarkers. The nucleic acid proximity-based methods proximity ligation and proximity extension assays have, with their dual repor...

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Veröffentlicht in:	PloS one 2014-04, Vol.9 (4), p.e95192-e95192
Hauptverfasser:	Assarsson, Erika, Lundberg, Martin, Holmquist, Göran, Björkesten, Johan, Thorsen, Stine Bucht, Ekman, Daniel, Eriksson, Anna, Rennel Dickens, Emma, Ohlsson, Sandra, Edfeldt, Gabriella, Andersson, Ann-Catrin, Lindstedt, Patrik, Stenvang, Jan, Gullberg, Mats, Fredriksson, Simon
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Antibodies Antigens Binding sites Biology Biology and Life Sciences Biomarkers Blood Proteins - metabolism Breast cancer Cloning Cross Reactions Cross-reactivity Deoxyribonucleic acid Design modifications DNA DNA polymerase DNA-Directed DNA Polymerase - metabolism Dried Blood Spot Testing Enzyme Stability Female Health care Heterografts Humans Immunoassay Immunoassay - methods Immunoglobulins Medical research Medicine and Health Sciences Mice, Nude Multiplexing Oligonucleotides - metabolism Polymerase Chain Reaction - methods Protein research Proteins Proteomics Proximity Reagents Reference services Reproducibility Research and Analysis Methods Sensitivity Sensitivity and Specificity Spots Temperature Xenografts
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