Transcriptomic and functional analysis of NaCl-induced stress in Enterococcus faecalis

The robust physiology of Enterococcus faecalis facilitates tolerance to various stresses. We here report the transcriptional response of E. faecalis V583 to growth in the presence of 6.5% NaCl. Among the early responses observed was an immediate down-regulation of mscL, accompanied by an up-regulati...

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Veröffentlicht in:	PloS one 2014-04, Vol.9 (4), p.e94571
Hauptverfasser:	Solheim, Margrete, La Rosa, Sabina Leanti, Mathisen, Thomas, Snipen, Lars G, Nes, Ingolf F, Brede, Dag Anders
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial proteins Bacterial Proteins - genetics Bacterial Proteins - metabolism Biofilms Biology and Life Sciences Biosynthesis Cell Membrane - drug effects Cell Membrane - metabolism Cell Wall - drug effects Cell Wall - metabolism Complementation Cytoprotection - drug effects Cytoprotection - genetics Enterococcus faecalis Enterococcus faecalis - drug effects Enterococcus faecalis - genetics Enterococcus faecalis - growth & development Enterococcus faecalis - physiology Food Functional analysis Gelatinase Gene expression Gene Expression Profiling Gene Expression Regulation, Bacterial - drug effects Gene regulation Genetic analysis Genetic Complementation Test Glycine Glycine betaine Gram-positive bacteria Human performance Humans Immunological tolerance Laboratories Life sciences Medicine and Health Sciences Microbial Sensitivity Tests Mutants Nosocomial infections Oligonucleotide Array Sequence Analysis Osmolar Concentration Pathogenesis Peptides Physiology Plasmids Potassium Promoter Regions, Genetic - genetics Reproducibility of Results Rhamnose - metabolism Salts Sodium chloride Sodium Chloride - pharmacology Stress Stress, Physiological - drug effects Stress, Physiological - genetics Stresses Time Factors Transcription Transcription, Genetic - drug effects Transcriptome - drug effects Transcriptome - genetics Virulence
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