Chronic high fructose intake reduces serum 1,25 (OH)2D3 levels in calcium-sufficient rodents

Excessive fructose consumption inhibits adaptive increases in intestinal Ca2+ transport in lactating and weanling rats with increased Ca2+ requirements by preventing the increase in serum levels of 1,25(OH)2D3. Here we tested the hypothesis that chronic fructose intake decreases 1,25(OH)2D3 levels i...

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Veröffentlicht in:	PloS one 2014-04, Vol.9 (4), p.e93611
Hauptverfasser:	Douard, Veronique, Patel, Chirag, Lee, Jacklyn, Tharabenjasin, Phuntila, Williams, Edek, Fritton, J Christopher, Sabbagh, Yves, Ferraris, Ronaldo P
Format:	Artikel
Sprache:	eng
Schlagworte:	25-Hydroxyvitamin D3 1-alpha-Hydroxylase - metabolism Animals Biological Transport - drug effects Biology and Life Sciences Biomedical engineering Calcitriol Calcitriol - blood Calcium Calcium (dietary) Calcium - metabolism Calcium phosphates Calcium transport Calcium, Dietary - pharmacology Carbohydrates Diet Endocrinology Feeding Behavior - drug effects Fibroblast growth factor 23 Fructose Fructose - pharmacology Gene expression Glucose Glucose - pharmacology Health sciences Homeostasis Hydroxylase Hypotheses Intestine Intestines - drug effects Intestines - metabolism Kidney diseases Kidneys Male Medical schools Membrane Transport Proteins - metabolism Metabolism Mice Mice, Inbred C57BL Parathyroid Parathyroid hormone Pharmacology Phosphates Physiology Rats Rodents Serum levels Starch Sugar Time Factors Vitamin D Vitamin deficiency Weaning
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