Simultaneous measurement of thirteen steroid hormones in women with polycystic ovary syndrome and control women using liquid chromatography-tandem mass spectrometry

The measurement of adrenal and ovarian androgens in women with PCOS has been difficult based on poor specificity and sensitivity of assays in the female range. Women with PCOS (NIH criteria; n = 52) and control subjects with 25-35 day menstrual cycles, no evidence of hyperandrogenism and matched for...

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Veröffentlicht in:	PloS one 2014-04, Vol.9 (4), p.e93805-e93805
Hauptverfasser:	Keefe, Candace C, Goldman, Mildred M, Zhang, Ke, Clarke, Nigel, Reitz, Richard E, Welt, Corrine K
Format:	Artikel
Sprache:	eng
Schlagworte:	17-alpha-Hydroxyprogesterone - blood Accuracy Acne Adolescent Adult Androgens Androstenedione Androstenedione - blood Biology and Life Sciences Blood Body mass Body mass index Chromatography Chromatography, Liquid Corticosterone Cortisol Female Hormones Hormones - blood Humans Hydrocortisone Hyperandrogenism - blood Immunoassay Intubation Liquid chromatography Mass spectrometry Mass spectroscopy Medicine and Health Sciences Menstruation Polycystic ovary syndrome Polycystic Ovary Syndrome - blood Progesterone Research and Analysis Methods Scientific imaging Spectroscopy Steroid hormones Steroids Steroids - blood Tandem Mass Spectrometry Testosterone Testosterone - blood Young Adult
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