Characterization of human pseudogene-derived non-coding RNAs for functional potential

Thousands of pseudogenes exist in the human genome and many are transcribed, but their functional potential remains elusive and understudied. To explore these issues systematically, we first developed a computational pipeline to identify transcribed pseudogenes from RNA-Seq data. Applying the pipeli...

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Veröffentlicht in:	PloS one 2014-04, Vol.9 (4), p.e93972-e93972
Hauptverfasser:	Guo, Xingyi, Lin, Mingyan, Rockowitz, Shira, Lachman, Herbert M, Zheng, Deyou
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Antisense RNA Biology and Life Sciences Biotechnology Cell growth Cell lines Chromatin Computer and Information Sciences Computer applications DNA methylation Enrichment Epigenetic inheritance Epigenetics Gene expression Genes Genome, Human Genomes Genomics Heterochromatin Human tissues Humans Lysine Medicine Methyltransferase MicroRNAs Neurosciences Nucleotide sequence Post-transcription Proteins Pseudogenes PTEN protein Ribonucleic acid RNA RNA, Untranslated Tissues Transcription, Genetic
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