Incidence and predictors of first line antiretroviral regimen modification in western Kenya

Limited antiretroviral treatment regimens in resource-limited settings require long-term sustainability of patients on the few available options. We evaluated the incidence and predictors of combined antiretroviral treatment (cART) modifications, in an outpatient cohort of 955 patients who initiated...

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Veröffentlicht in:	PloS one 2014-04, Vol.9 (4), p.e93106-e93106
Hauptverfasser:	Inzaule, Seth, Otieno, Juliana, Kalyango, Joan, Nafisa, Lillian, Kabugo, Charles, Nalusiba, Josephine, Kwaro, Daniel, Zeh, Clement, Karamagi, Charles
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome Adult Age Factors AIDS Analysis Anti-Retroviral Agents - administration & dosage Antiretroviral agents Antiretroviral drugs Antiviral agents Biology and Life Sciences CD4 antigen CD4 Lymphocyte Count Disease control Disease prevention Dosage and administration Drug dosages Drug therapy Drug Therapy, Combination - methods Epidemiology Factor analysis Female Follow-Up Studies Health aspects Highly active antiretroviral therapy HIV HIV infection HIV Infections - blood HIV Infections - drug therapy HIV Infections - epidemiology HIV Infections - immunology Hospitals Human immunodeficiency virus Humans Immunology Incidence Infections Kenya Male Medical prognosis Medical research Medical schools Medicine and health sciences Patients Poisson density functions Regression analysis Regression models Research and Analysis Methods Retrospective Studies Risk analysis Risk Factors Statistical analysis Stavudine Sustainability Tenofovir Toxicity Zidovudine
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