Redistribution of ionotropic glutamate receptors detected by laser microdissection of the rat dentate gyrus 48 h following LTP induction in vivo

The persistence and input specificity of long-term potentiation (LTP) make it attractive as a mechanism of information storage. In its initial phase, both in vivo and in vitro studies have shown that LTP is associated with increased membrane localization of AMPA receptor subunits, but the molecular...

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Veröffentlicht in:	PloS one 2014-03, Vol.9 (3), p.e92972-e92972
Hauptverfasser:	Kennard, Jeremy T T, Guévremont, Diane, Mason-Parker, Sara E, Abraham, Wickliffe C, Williams, Joanna M
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Animals Biology and Life Sciences Brain research Dentate gyrus Dentate Gyrus - cytology Dentate Gyrus - metabolism Dentate Gyrus - physiology Electrodes Gene Expression Regulation Glutamate Glutamic acid receptors (ionotropic) In vivo methods and tests Information storage Information storage and retrieval Laser Capture Microdissection Lasers Localization Long-Term Potentiation Male Medical research N-Methyl-D-aspartic acid receptors Postsynaptic density Potentiation Protein expression Protein Subunits - metabolism Protein synthesis Protein Transport Proteins Rats Rats, Sprague-Dawley Receptors Receptors, AMPA - metabolism Receptors, N-Methyl-D-Aspartate - metabolism Research and Analysis Methods Rodents Surgery Synapses Synapses - metabolism Time Factors Tubulin Tubulin - metabolism α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors
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