uPARAP function in cutaneous wound repair

Optimal skin wound healing relies on tight balance between collagen synthesis and degradation in new tissue formation and remodeling phases. The endocytic receptor uPARAP regulates collagen uptake and intracellular degradation. In this study we examined cutaneous wound repair response of uPARAP null...

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Veröffentlicht in:	PloS one 2014-03, Vol.9 (3), p.e92660-e92660
Hauptverfasser:	Rohani, Maryam G, Chow, Yu-Hua, Razumova, Maria V, Ash, Samuel, Hung, Chi F, Schnapp, Lynn M
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Biochemical analysis Biology Biology and Life Sciences Biomechanical Phenomena Biopsy Cancer Collagen Collagen - metabolism Critical care Degradation Epithelial Cells - cytology Fibroblasts Gene expression Gene Expression Regulation Genetic aspects Histology Intracellular Medicine Medicine and Health Sciences Membrane Glycoproteins - deficiency Membrane Glycoproteins - genetics Membrane Glycoproteins - metabolism Mice Mice, Inbred C57BL Receptors, Cell Surface - deficiency Receptors, Cell Surface - genetics Receptors, Cell Surface - metabolism Repair Research and Analysis Methods Rodents Skin Skin - cytology Skin - metabolism Skin Physiological Phenomena Stiffness Transcription Wound care Wound Healing
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