Performance comparison between rapid sequencing platforms for ultra-low coverage sequencing strategy

Ultra-low coverage sequencing (ULCS) is one of the most promising strategies for sequencing based clinical application. These clinical applications, especially prenatal diagnosis, have a strict requirement of turn-around-time; therefore, the application of ULCS is restricted by current high throughp...

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Veröffentlicht in:	PloS one 2014-03, Vol.9 (3), p.e92192-e92192
Hauptverfasser:	Chen, Shengpei, Li, Sheng, Xie, Weiwei, Li, Xuchao, Zhang, Chunlei, Jiang, Haojun, Zheng, Jing, Pan, Xiaoyu, Zheng, Hancheng, Liu, Jia Sophie, Deng, Yongqiang, Chen, Fang, Jiang, Hui
Format:	Artikel
Sprache:	eng
Schlagworte:	Abortion Aneuploidy Base Composition - genetics Bioinformatics Biology and Life Sciences Cell culture Clinical trials Data processing Deoxyribonucleic acid DNA Engineering Female Fetuses Gene expression Genomes Genomics High-Throughput Nucleotide Sequencing - methods High-Throughput Nucleotide Sequencing - standards Humans Laboratories Male Medical diagnosis Medicine and Health Sciences Miscarriage Next-generation sequencing Platforms Pregnant women Prenatal diagnosis Sex Chromosomes - genetics Therapeutic applications
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