A novel and effective cancer immunotherapy mouse model using antigen-specific B cells selected in vitro

Immunotherapies such as adoptive transfer of T cells or natural killer cells, or monoclonal antibody (MoAb) treatment have recently been recognized as effective means to treat cancer patients. However, adoptive transfer of B cells or plasma cells producing tumor-specific antibodies has not been appl...

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Veröffentlicht in:	PloS one 2014-03, Vol.9 (3), p.e92732-e92732
Hauptverfasser:	Moutai, Tatsuya, Yamana, Hideyuki, Nojima, Takuya, Kitamura, Daisuke
Format:	Artikel
Sprache:	eng
Schlagworte:	Adoptive immunotherapy Adoptive transfer Animals Antigens B-Lymphocytes - immunology Biology and Life Sciences Bone marrow Cancer Cancer immunotherapy Cancer metastasis Cancer treatment CD95 antigen Cell culture Cell death Cell survival Drug development Drug therapy Drugs Fas antigen Immunoglobulin G Immunoglobulins Immunotherapy Immunotherapy - methods Immunotherapy, Adoptive - methods Lungs Lymphocyte receptors Lymphocytes Lymphocytes B Lymphocytes T Medicine and Health Sciences Melanoma Melanoma - therapy Metastases Mice Mice, Mutant Strains Monoclonal antibodies Natural killer cells Patients Plasma cells Receptors T cell receptors
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