Analysis of serum miRNA profiles of myasthenia gravis patients

Myasthenia gravis (MG) is an autoimmune disease characterized by the presence of autoantibodies, mainly against the acetylcholine receptor (AChR). The mechanisms triggering and maintaining this chronic disease are unknown. MiRNAs are regulatory molecules that play a key role in the immune system and...

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Veröffentlicht in:	PloS one 2014-03, Vol.9 (3), p.e91927-e91927
Hauptverfasser:	Nogales-Gadea, Gisela, Ramos-Fransi, Alba, Suárez-Calvet, Xavier, Navas, Miquel, Rojas-García, Ricard, Mosquera, Jose Luis, Díaz-Manera, Jordi, Querol, Luis, Gallardo, Eduard, Illa, Isabel
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine receptors Adult Age of Onset Aged Aged, 80 and over Analysis Antigens Autoantibodies Autoimmune diseases Autoimmunity B cells Biology and Life Sciences Biomarkers Cell survival Chronic diseases Cluster Analysis Female Gene expression Gene Expression Profiling Humans Immune system Immunoglobulins Immunosuppressive Agents - therapeutic use Leukemia Leukocytes (mononuclear) Liver cancer Lymphocytes B Male Medical prognosis Medical research Medicine and Health Sciences MicroRNA MicroRNAs MicroRNAs - blood MicroRNAs - genetics Middle Aged miRNA Myasthenia Myasthenia gravis Myasthenia Gravis - blood Myasthenia Gravis - genetics Myasthenia Gravis - therapy Neuromuscular diseases Neuromuscular junctions Pathogenesis Patients Subgroups Thymectomy Thymoma Treatment Outcome
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