A variant in the neuropeptide receptor npr-1 is a major determinant of Caenorhabditis elegans growth and physiology

The mechanistic basis for how genetic variants cause differences in phenotypic traits is often elusive. We identified a quantitative trait locus in Caenorhabditis elegans that affects three seemingly unrelated phenotypic traits: lifetime fecundity, adult body size, and susceptibility to the human pa...

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