A novel single pulsed electromagnetic field stimulates osteogenesis of bone marrow mesenchymal stem cells and bone repair

Pulsed electromagnetic field (PEMF) has been successfully applied to accelerate fracture repair since 1979. Recent studies suggest that PEMF might be used as a nonoperative treatment for the early stages of osteonecrosis. However, PEMF treatment requires a minimum of ten hours per day for the durati...

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Veröffentlicht in:	PloS one 2014-03, Vol.9 (3), p.e91581-e91581
Hauptverfasser:	Fu, Yin-Chih, Lin, Chih-Chun, Chang, Je-Ken, Chen, Chung-Hwan, Tai, I-Chun, Wang, Gwo-Jaw, Ho, Mei-Ling
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaline Phosphatase - metabolism Animals Biocompatibility Biology Biomedical materials Bone growth Bone healing Bone marrow Bone Regeneration Bone surgery Bones Calcification, Physiologic Callus Cell cycle Cell Differentiation Cell proliferation Cell Proliferation - radiation effects Cytotoxicity Differentiation Electromagnetic fields Electromagnetic Fields - adverse effects Electromagnetism Engineering Enzyme Activation FDA approval Female Fractures Grafting Humans Immunohistochemistry In vivo methods and tests Male Medicine Mesenchymal stem cells Mesenchymal Stromal Cells - cytology Mesenchymal Stromal Cells - radiation effects Mesenchyme Mice Mineralization Osteogenesis Osteogenesis - radiation effects Osteonecrosis Physics Physiology Repair Stem cell transplantation Stem cells Surgery Vascularization
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