A population-based approach to study the impact of PROP perception on food liking in populations along the Silk Road
Taste is one of the main factors determining food choices. Differences in PROP bitter taste perception have been implicated in individual differences in food preferences and selection. The present study examined associations between, PROP phenotypes, self-reported food liking and TAS2R38 polymorphis...
Gespeichert in:
| Veröffentlicht in: | PloS one 2014-03, Vol.9 (3), p.e91716 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 3 |
| container_start_page | e91716 |
| container_title | PloS one |
| container_volume | 9 |
| creator | Robino, Antonietta Mezzavilla, Massimo Pirastu, Nicola Dognini, Maddalena Tepper, Beverly J Gasparini, Paolo |
| description | Taste is one of the main factors determining food choices. Differences in PROP bitter taste perception have been implicated in individual differences in food preferences and selection. The present study examined associations between, PROP phenotypes, self-reported food liking and TAS2R38 polymorphisms, the major gene implicated in PROP bitterness, in six different populations of the Caucasus and Central Asia, located along the ancient Silk Road. Differences in the distribution of PROP phenotypes across populations were detected, with a higher frequency of super tasters in Tajikistan (31.3%) and Armenia (39.0%) and a higher frequency of non tasters in Georgia (50.9%). While no relationships were observed between PROP phenotypes and food liking using standard statistical tests, we used an approach based on comparison of distance matrices derived from these data. The first matrix compared the food liking ratings of each population to all others pairwise using the Kruskal-Wallis test (at p |
| doi_str_mv | 10.1371/journal.pone.0091716 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_plos_</sourceid><recordid>TN_cdi_plos_journals_1507248153</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A478769352</galeid><doaj_id>oai_doaj_org_article_8f8cb07895324592b419c540f34b9ff0</doaj_id><sourcerecordid>A478769352</sourcerecordid><originalsourceid>FETCH-LOGICAL-c692t-bbdb12aeaa1877527a78723b07df9bd91243d586eb5908733bb6e184284bdaec3</originalsourceid><addsrcrecordid>eNqNkltr2zAcxc3YWLtu32BsgsFgD8l0sWXpZRDKLoFCSrrtVejmRK1juZI81m8_pXFLDBsMCyz--p0jcThF8RrBOSI1-njth9DJdt77zs4h5KhG9ElxijjBM4oheXq0PylexHgNYUUYpc-LE1xSTBGnp0VagN73QyuT891MyWgNkH0fvNRbkDyIaTB3IG0tcLte6gR8Ay7Xq0vQ26Btv1eBvBrvDWjdjes2wHVHlhHI1ufh3uHKtTdg7aV5WTxrZBvtq_F_Vvz48vn7-bfZxerr8nxxMdOU4zRTyiiEpZUSsbqucC1rVmOiYG0argxHuCSmYtSqikNWE6IUtYiVmJXKSKvJWfH24Nu3PooxsChQBWtcMlSRTCwPhPHyWvTB7WS4E146cT_wYSNkSE63VrCG6Xw14xXBZcWxKhHXVQkbUireNDB7fRpvG9TOGm27FGQ7MZ2edG4rNv6XINmyYnuDd6NB8LeDjekfTx6pjcyvcl3js5neuajFoswBUU4qnKn5X6j8GbtzOlemcXk-EXyYCDKT7O-0kUOMYnm1_n929XPKvj9it1a2aRt9O9yXYwqWB1AHH2OwzWNyCIp94x_SEPvGi7HxWfbmOPVH0UPFyR9JDvuv</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1507248153</pqid></control><display><type>article</type><title>A population-based approach to study the impact of PROP perception on food liking in populations along the Silk Road</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Public Library of Science (PLoS)</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><creator>Robino, Antonietta ; Mezzavilla, Massimo ; Pirastu, Nicola ; Dognini, Maddalena ; Tepper, Beverly J ; Gasparini, Paolo</creator><contributor>Simon, Sidney Arthur</contributor><creatorcontrib>Robino, Antonietta ; Mezzavilla, Massimo ; Pirastu, Nicola ; Dognini, Maddalena ; Tepper, Beverly J ; Gasparini, Paolo ; Simon, Sidney Arthur</creatorcontrib><description>Taste is one of the main factors determining food choices. Differences in PROP bitter taste perception have been implicated in individual differences in food preferences and selection. The present study examined associations between, PROP phenotypes, self-reported food liking and TAS2R38 polymorphisms, the major gene implicated in PROP bitterness, in six different populations of the Caucasus and Central Asia, located along the ancient Silk Road. Differences in the distribution of PROP phenotypes across populations were detected, with a higher frequency of super tasters in Tajikistan (31.3%) and Armenia (39.0%) and a higher frequency of non tasters in Georgia (50.9%). While no relationships were observed between PROP phenotypes and food liking using standard statistical tests, we used an approach based on comparison of distance matrices derived from these data. The first matrix compared the food liking ratings of each population to all others pairwise using the Kruskal-Wallis test (at p<0.00063), and the second one compared the distribution of PROP phenotypes across all populations in a similar manner calculating the chi-square statistic as a distance measure. A strong correlation between the two matrices was found (Mantel test: r = 0.67, p-value = 0.03), suggesting that the pattern of food liking across populations was closely related to the distribution of PROP phenotypes. This same relationship was not observed when TAS2R38 genotypes were substituted for PROP phenotypes in this analysis. Our data suggest that a population-based approach utilizing distance matrices is a useful technique for detecting PROP-related differences in food liking and can be applied to other taste phenotypes.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0091716</identifier><identifier>PMID: 24626196</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Armenia ; Azerbaijan ; Biology ; Bitter taste ; Bitterness ; Brassica ; Correlation analysis ; Data processing ; Distance measurement ; Food ; Food habits ; Food preferences ; Food selection ; Genetic aspects ; Genetic Association Studies ; Genetic polymorphisms ; Genotype ; Genotypes ; Haplotypes ; Humans ; Medicine ; Perception ; Polymorphism, Single Nucleotide ; Population (statistical) ; Population studies ; Population-based studies ; Propylthiouracil - pharmacology ; Receptors, G-Protein-Coupled - genetics ; Statistical analysis ; Statistical tests ; Tajikistan ; Taste ; Taste - genetics ; Taste perception ; Taste Perception - genetics ; Taste receptors ; Uzbekistan</subject><ispartof>PloS one, 2014-03, Vol.9 (3), p.e91716</ispartof><rights>COPYRIGHT 2014 Public Library of Science</rights><rights>2014 Robino et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2014 Robino et al 2014 Robino et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c692t-bbdb12aeaa1877527a78723b07df9bd91243d586eb5908733bb6e184284bdaec3</citedby><cites>FETCH-LOGICAL-c692t-bbdb12aeaa1877527a78723b07df9bd91243d586eb5908733bb6e184284bdaec3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953580/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953580/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,728,781,785,865,886,2103,2929,23871,27929,27930,53796,53798</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24626196$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Simon, Sidney Arthur</contributor><creatorcontrib>Robino, Antonietta</creatorcontrib><creatorcontrib>Mezzavilla, Massimo</creatorcontrib><creatorcontrib>Pirastu, Nicola</creatorcontrib><creatorcontrib>Dognini, Maddalena</creatorcontrib><creatorcontrib>Tepper, Beverly J</creatorcontrib><creatorcontrib>Gasparini, Paolo</creatorcontrib><title>A population-based approach to study the impact of PROP perception on food liking in populations along the Silk Road</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>Taste is one of the main factors determining food choices. Differences in PROP bitter taste perception have been implicated in individual differences in food preferences and selection. The present study examined associations between, PROP phenotypes, self-reported food liking and TAS2R38 polymorphisms, the major gene implicated in PROP bitterness, in six different populations of the Caucasus and Central Asia, located along the ancient Silk Road. Differences in the distribution of PROP phenotypes across populations were detected, with a higher frequency of super tasters in Tajikistan (31.3%) and Armenia (39.0%) and a higher frequency of non tasters in Georgia (50.9%). While no relationships were observed between PROP phenotypes and food liking using standard statistical tests, we used an approach based on comparison of distance matrices derived from these data. The first matrix compared the food liking ratings of each population to all others pairwise using the Kruskal-Wallis test (at p<0.00063), and the second one compared the distribution of PROP phenotypes across all populations in a similar manner calculating the chi-square statistic as a distance measure. A strong correlation between the two matrices was found (Mantel test: r = 0.67, p-value = 0.03), suggesting that the pattern of food liking across populations was closely related to the distribution of PROP phenotypes. This same relationship was not observed when TAS2R38 genotypes were substituted for PROP phenotypes in this analysis. Our data suggest that a population-based approach utilizing distance matrices is a useful technique for detecting PROP-related differences in food liking and can be applied to other taste phenotypes.</description><subject>Armenia</subject><subject>Azerbaijan</subject><subject>Biology</subject><subject>Bitter taste</subject><subject>Bitterness</subject><subject>Brassica</subject><subject>Correlation analysis</subject><subject>Data processing</subject><subject>Distance measurement</subject><subject>Food</subject><subject>Food habits</subject><subject>Food preferences</subject><subject>Food selection</subject><subject>Genetic aspects</subject><subject>Genetic Association Studies</subject><subject>Genetic polymorphisms</subject><subject>Genotype</subject><subject>Genotypes</subject><subject>Haplotypes</subject><subject>Humans</subject><subject>Medicine</subject><subject>Perception</subject><subject>Polymorphism, Single Nucleotide</subject><subject>Population (statistical)</subject><subject>Population studies</subject><subject>Population-based studies</subject><subject>Propylthiouracil - pharmacology</subject><subject>Receptors, G-Protein-Coupled - genetics</subject><subject>Statistical analysis</subject><subject>Statistical tests</subject><subject>Tajikistan</subject><subject>Taste</subject><subject>Taste - genetics</subject><subject>Taste perception</subject><subject>Taste Perception - genetics</subject><subject>Taste receptors</subject><subject>Uzbekistan</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>DOA</sourceid><recordid>eNqNkltr2zAcxc3YWLtu32BsgsFgD8l0sWXpZRDKLoFCSrrtVejmRK1juZI81m8_pXFLDBsMCyz--p0jcThF8RrBOSI1-njth9DJdt77zs4h5KhG9ElxijjBM4oheXq0PylexHgNYUUYpc-LE1xSTBGnp0VagN73QyuT891MyWgNkH0fvNRbkDyIaTB3IG0tcLte6gR8Ay7Xq0vQ26Btv1eBvBrvDWjdjes2wHVHlhHI1ufh3uHKtTdg7aV5WTxrZBvtq_F_Vvz48vn7-bfZxerr8nxxMdOU4zRTyiiEpZUSsbqucC1rVmOiYG0argxHuCSmYtSqikNWE6IUtYiVmJXKSKvJWfH24Nu3PooxsChQBWtcMlSRTCwPhPHyWvTB7WS4E146cT_wYSNkSE63VrCG6Xw14xXBZcWxKhHXVQkbUireNDB7fRpvG9TOGm27FGQ7MZ2edG4rNv6XINmyYnuDd6NB8LeDjekfTx6pjcyvcl3js5neuajFoswBUU4qnKn5X6j8GbtzOlemcXk-EXyYCDKT7O-0kUOMYnm1_n929XPKvj9it1a2aRt9O9yXYwqWB1AHH2OwzWNyCIp94x_SEPvGi7HxWfbmOPVH0UPFyR9JDvuv</recordid><startdate>20140313</startdate><enddate>20140313</enddate><creator>Robino, Antonietta</creator><creator>Mezzavilla, Massimo</creator><creator>Pirastu, Nicola</creator><creator>Dognini, Maddalena</creator><creator>Tepper, Beverly J</creator><creator>Gasparini, Paolo</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20140313</creationdate><title>A population-based approach to study the impact of PROP perception on food liking in populations along the Silk Road</title><author>Robino, Antonietta ; Mezzavilla, Massimo ; Pirastu, Nicola ; Dognini, Maddalena ; Tepper, Beverly J ; Gasparini, Paolo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c692t-bbdb12aeaa1877527a78723b07df9bd91243d586eb5908733bb6e184284bdaec3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Armenia</topic><topic>Azerbaijan</topic><topic>Biology</topic><topic>Bitter taste</topic><topic>Bitterness</topic><topic>Brassica</topic><topic>Correlation analysis</topic><topic>Data processing</topic><topic>Distance measurement</topic><topic>Food</topic><topic>Food habits</topic><topic>Food preferences</topic><topic>Food selection</topic><topic>Genetic aspects</topic><topic>Genetic Association Studies</topic><topic>Genetic polymorphisms</topic><topic>Genotype</topic><topic>Genotypes</topic><topic>Haplotypes</topic><topic>Humans</topic><topic>Medicine</topic><topic>Perception</topic><topic>Polymorphism, Single Nucleotide</topic><topic>Population (statistical)</topic><topic>Population studies</topic><topic>Population-based studies</topic><topic>Propylthiouracil - pharmacology</topic><topic>Receptors, G-Protein-Coupled - genetics</topic><topic>Statistical analysis</topic><topic>Statistical tests</topic><topic>Tajikistan</topic><topic>Taste</topic><topic>Taste - genetics</topic><topic>Taste perception</topic><topic>Taste Perception - genetics</topic><topic>Taste receptors</topic><topic>Uzbekistan</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Robino, Antonietta</creatorcontrib><creatorcontrib>Mezzavilla, Massimo</creatorcontrib><creatorcontrib>Pirastu, Nicola</creatorcontrib><creatorcontrib>Dognini, Maddalena</creatorcontrib><creatorcontrib>Tepper, Beverly J</creatorcontrib><creatorcontrib>Gasparini, Paolo</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Materials Science Collection</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Engineering Collection</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Robino, Antonietta</au><au>Mezzavilla, Massimo</au><au>Pirastu, Nicola</au><au>Dognini, Maddalena</au><au>Tepper, Beverly J</au><au>Gasparini, Paolo</au><au>Simon, Sidney Arthur</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A population-based approach to study the impact of PROP perception on food liking in populations along the Silk Road</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2014-03-13</date><risdate>2014</risdate><volume>9</volume><issue>3</issue><spage>e91716</spage><pages>e91716-</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>Taste is one of the main factors determining food choices. Differences in PROP bitter taste perception have been implicated in individual differences in food preferences and selection. The present study examined associations between, PROP phenotypes, self-reported food liking and TAS2R38 polymorphisms, the major gene implicated in PROP bitterness, in six different populations of the Caucasus and Central Asia, located along the ancient Silk Road. Differences in the distribution of PROP phenotypes across populations were detected, with a higher frequency of super tasters in Tajikistan (31.3%) and Armenia (39.0%) and a higher frequency of non tasters in Georgia (50.9%). While no relationships were observed between PROP phenotypes and food liking using standard statistical tests, we used an approach based on comparison of distance matrices derived from these data. The first matrix compared the food liking ratings of each population to all others pairwise using the Kruskal-Wallis test (at p<0.00063), and the second one compared the distribution of PROP phenotypes across all populations in a similar manner calculating the chi-square statistic as a distance measure. A strong correlation between the two matrices was found (Mantel test: r = 0.67, p-value = 0.03), suggesting that the pattern of food liking across populations was closely related to the distribution of PROP phenotypes. This same relationship was not observed when TAS2R38 genotypes were substituted for PROP phenotypes in this analysis. Our data suggest that a population-based approach utilizing distance matrices is a useful technique for detecting PROP-related differences in food liking and can be applied to other taste phenotypes.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>24626196</pmid><doi>10.1371/journal.pone.0091716</doi><tpages>e91716</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1932-6203 |
| ispartof | PloS one, 2014-03, Vol.9 (3), p.e91716 |
| issn | 1932-6203 1932-6203 |
| language | eng |
| recordid | cdi_plos_journals_1507248153 |
| source | MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Public Library of Science (PLoS); PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Armenia Azerbaijan Biology Bitter taste Bitterness Brassica Correlation analysis Data processing Distance measurement Food Food habits Food preferences Food selection Genetic aspects Genetic Association Studies Genetic polymorphisms Genotype Genotypes Haplotypes Humans Medicine Perception Polymorphism, Single Nucleotide Population (statistical) Population studies Population-based studies Propylthiouracil - pharmacology Receptors, G-Protein-Coupled - genetics Statistical analysis Statistical tests Tajikistan Taste Taste - genetics Taste perception Taste Perception - genetics Taste receptors Uzbekistan |
| title | A population-based approach to study the impact of PROP perception on food liking in populations along the Silk Road |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-15T05%3A44%3A39IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20population-based%20approach%20to%20study%20the%20impact%20of%20PROP%20perception%20on%20food%20liking%20in%20populations%20along%20the%20Silk%20Road&rft.jtitle=PloS%20one&rft.au=Robino,%20Antonietta&rft.date=2014-03-13&rft.volume=9&rft.issue=3&rft.spage=e91716&rft.pages=e91716-&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0091716&rft_dat=%3Cgale_plos_%3EA478769352%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1507248153&rft_id=info:pmid/24626196&rft_galeid=A478769352&rft_doaj_id=oai_doaj_org_article_8f8cb07895324592b419c540f34b9ff0&rfr_iscdi=true |