Neutrophil extracellular traps as innate immune reaction against the emerging apicomplexan parasite Besnoitia besnoiti

Besnoitia besnoiti infection in cattle is an important emerging protozoan disease in Europe causing economic losses and severe clinical signs, such as generalized dermatitis, orchitis, and vulvitis in affected animals. Neutrophil extracellular trap (NET) formation was recently demonstrated as an imp...

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Veröffentlicht in:	PloS one 2014-03, Vol.9 (3), p.e91415-e91415
Hauptverfasser:	Muñoz Caro, Tamara, Hermosilla, Carlos, Silva, Liliana M R, Cortes, Helder, Taubert, Anja
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Antimicrobial agents Biology Cattle Cattle Diseases - immunology Cattle Diseases - metabolism Cattle Diseases - parasitology Coccidia - immunology Coccidiosis - veterinary Deoxyribonuclease Deoxyribonucleic acid Dermatitis DNA DNA binding proteins Economic impact Eimeria Elastase Electron microscopy Entrapment Extracellular Traps - immunology Fluorescence Hermosilla Histones Host-Parasite Interactions - immunology Immune response Immune system Immunity, Innate Infection Infections Innate immunity Kinetics Leukocyte Elastase - metabolism Localization NAD(P)H oxidase NADPH Oxidases - metabolism Neutrophils Neutrophils - immunology Neutrophils - metabolism Neutrophils - ultrastructure Orchitis Oxidases Parasites Parasitic diseases Parasitology Peroxidase Peroxidase - metabolism Protozoa Reactive Oxygen Species Rodents Scanning electron microscopy Tachyzoites Toxoplasma gondii Veins & arteries Veterinary Science
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