BRAFV600E mutation and its association with clinicopathological features of colorectal cancer: a systematic review and meta-analysis

Colorectal cancer (CRC) is a heterogeneous disease with multiple underlying causative genetic mutations. The B-type Raf proto-oncogene (BRAF) plays an important role in the mitogen-activated protein kinase (MAPK) signaling cascade during CRC. The presence of BRAFV600E mutation can determine the resp...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	PloS one 2014, Vol.9 (3), p.e90607-e90607
Hauptverfasser:	Chen, Dong, Huang, Jun-Fu, Liu, Kai, Zhang, Li-Qun, Yang, Zhao, Chuai, Zheng-Ran, Wang, Yun-Xia, Shi, Da-Chuan, Huang, Qing, Fu, Wei-Ling
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol use Biology Colorectal cancer Colorectal Neoplasms - genetics Colorectal Neoplasms - pathology Genetic Association Studies Genetic Markers - genetics Humans Medicine Meta-analysis Mutation Mutation, Missense - genetics Odds Ratio Proto-Oncogene Proteins B-raf - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!