Functional Fcgamma receptor polymorphisms are associated with human allergy

IgG Fc receptors (FcγRs) play important roles in immune responses. It is not clear whether FcγR receptors play a role in human asthma and allergy. The aim of current study was to investigate whether functional single nucleotide polymorphisms (SNPs) of FcγR genes (FCGR) are associated with human asth...

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Veröffentlicht in:	PloS one 2014-02, Vol.9 (2), p.e89196-e89196
Hauptverfasser:	Wu, Jianming, Lin, Rui, Huang, Jinhai, Guan, Weihua, Oetting, William S, Sriramarao, P, Blumenthal, Malcolm N
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Alleles Allergies Analysis Asthma Asthma - genetics Atopy Biology Child Defects Deoxyribonucleic acid DNA Fc receptors Female Genes Genetic aspects Genetic Association Studies Genetic Predisposition to Disease Genomes Genotype Glutamine Humans Hypersensitivity Hypersensitivity - genetics Immune response Immunoglobulin E Immunoglobulin G Immunoglobulins Inflammatory diseases Lupus Male Medicine Middle Aged Pathogenesis Phenotype Phosphoproteins Polymorphism, Single Nucleotide Receptors Receptors, IgG - genetics Regression analysis Risk Factors Single nucleotide polymorphisms Single-nucleotide polymorphism Studies Young Adult
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