Oligodendroglial p130Cas is a target of Fyn kinase involved in process formation, cell migration and survival

Oligodendrocytes are the myelinating glial cells of the central nervous system. In the course of brain development, oligodendrocyte precursor cells migrate, scan the environment and differentiate into mature oligodendrocytes with multiple cellular processes which recognize and ensheath neuronal axon...

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Veröffentlicht in:	PloS one 2014-02, Vol.9 (2), p.e89423-e89423
Hauptverfasser:	Gonsior, Constantin, Binamé, Fabien, Frühbeis, Carsten, Bauer, Nina M, Hoch-Kraft, Peter, Luhmann, Heiko J, Trotter, Jacqueline, White, Robin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Axonogenesis Axons Axons - metabolism Biology Brain Cell adhesion & migration Cell migration Cell Movement - physiology Cell survival Cell Survival - physiology Cells, Cultured Central nervous system Cloning Crk-Associated Substrate Protein - metabolism Cytoskeleton Differentiation ErbB-2 protein Fibroblasts Fyn protein Glial cells Glial stem cells Growth factors Immunoglobulins Kinases Laboratories Mice Morphology Myelin Myelination Oligodendrocytes Oligodendroglia - cytology Oligodendroglia - metabolism Phosphorylation Physiology Plasmids Protein purification Protein-tyrosine kinase receptors Proteins Proto-Oncogene Proteins c-fyn - metabolism Reduction Rodents siRNA Spectrometry Target recognition Tyrosine
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