Cognitive and affective changes in mild to moderate Alzheimer's disease patients undergoing switch of cholinesterase inhibitors: a 6-month observational study

Patients with Alzheimer's disease after an initial response to cholinesterase inhibitors may complain a later lack of efficacy. This, in association with incident neuropsychiatric symptoms, may worsen patient quality of life. Thus, the switch to another cholinesterase inhibitor could represent...

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Veröffentlicht in:	PloS one 2014-02, Vol.9 (2), p.e89216-e89216
Hauptverfasser:	Spalletta, Gianfranco, Caltagirone, Carlo, Padovani, Alessandro, Sorbi, Sandro, Attar, Mahmood, Colombo, Delia, Cravello, Luca
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - drug therapy Alzheimer Disease - physiopathology Alzheimer's disease Apathy Apathy - drug effects Apathy - physiology Caregivers Cholinesterase Cholinesterase inhibitors Cholinesterase Inhibitors - therapeutic use Cognitive ability Cognitive Dysfunction - physiopathology Comorbidity Dementia Depression - physiopathology Drug Substitution Effectiveness Emotional behavior Ethics Health aspects Humans Inhibitors Italy Laboratories Medical research Medicine Mental depression Mood Disorders - physiopathology Neurodegenerative diseases Neurology Observational studies Patients Phenomenology Phenylcarbamates - therapeutic use Psychiatry Quality of life Rivastigmine Socioeconomic Factors Working groups
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