Global patterns of protein domain gain and loss in superkingdoms

Domains are modules within proteins that can fold and function independently and are evolutionarily conserved. Here we compared the usage and distribution of protein domain families in the free-living proteomes of Archaea, Bacteria and Eukarya and reconstructed species phylogenies while tracing the...

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Veröffentlicht in:	PLoS computational biology 2014-01, Vol.10 (1), p.e1003452-e1003452
Hauptverfasser:	Nasir, Arshan, Kim, Kyung Mo, Caetano-Anollés, Gustavo
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Archaea - genetics Archaeabacteria Bacteria Bacteria - genetics Biology Computational Biology Enzymes Evolution Evolution, Molecular Genomics Phylogenetics Phylogeny Physiological aspects Protein Folding Protein research Protein Structure, Tertiary Protein-protein interactions Proteins Proteome Proteomics - methods Reproducibility of Results Studies Symbiosis
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