Platelets and smooth muscle cells affecting the differentiation of monocytes

Atherosclerosis is characterised by the formation of plaques. Monocytes play a pivotal role in plaque development as they differentiate into foam cells, a component of the lipid core whilst smooth muscle cells (SMC) are the principal cell identified in the cap. Recently, the ability of monocytes to...

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Veröffentlicht in:	PloS one 2014-02, Vol.9 (2), p.e88172-e88172
Hauptverfasser:	Williams, Michelle W Y, Guiffre, Ann K, Fletcher, John P
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Antigens, CD - metabolism Aorta Arteriosclerosis Atherosclerosis Biology Biomarkers - metabolism Blood platelets Blood Platelets - cytology Blood Platelets - ultrastructure Bone marrow Cap formation Cell Differentiation Cells, Cultured Coculture Techniques Collagen Cytokines Differentiation Electron microscopy Endoplasmic reticulum Endothelium Environmental conditions Ethics Fibroblasts Fluorescent Antibody Technique Foam Foams Gene expression Growth factors Hospitals Humans Immunofluorescence Lipids Macrophages Markers Medicine Mesenchyme Microfilaments Monocytes Monocytes - cytology Monocytes - ultrastructure Muscles Myocytes, Smooth Muscle - cytology Myocytes, Smooth Muscle - ultrastructure Phenotype Plaques Platelets Polymerase chain reaction Real-Time Polymerase Chain Reaction Smooth muscle Stem cells Studies Surgery Wound healing
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