β-catenin enhances odontoblastic differentiation of dental pulp cells through activation of Runx2

An intense stimulus can cause death of odontoblasts and initiate odontoblastic differentiation of stem/progenitor cell populations of dental pulp cells (DPCs), which is followed by reparative dentin formation. However, the mechanism of odontoblastic differentiation during reparative dentin formation...

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Veröffentlicht in:	PloS one 2014-02, Vol.9 (2), p.e88890
Hauptverfasser:	Han, Nana, Zheng, Yong, Li, Ran, Li, Xianyu, Zhou, Mi, Niu, Yun, Zhang, Qi
Format:	Artikel
Sprache:	eng
Schlagworte:	Activation Adolescent Animals beta Catenin - metabolism Biology Cbfa-1 protein Cell Differentiation - drug effects Cement Core Binding Factor Alpha 1 Subunit - metabolism Dental pulp Dental Pulp - cytology Dentin Dentin - metabolism Differentiation Education Fractures Gene Knockdown Techniques Humans Immunofluorescence Laboratories Lithium Lithium chloride Lithium Chloride - pharmacology Male Medicine Odontoblasts Odontoblasts - cytology Perforation Progenitor cells Rats Rats, Wistar Science Stem cells Studies Teeth Time Factors Up-Regulation - drug effects β-catenin
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