Expression of miR-29c, miR-93, and miR-429 as potential biomarkers for detection of early stage non-small lung cancer

Altered expression of miRNA expression contributes to human carcinogenesis. This study was designed to detect aberrant miRNA expressions as a potential biomarker for early detection and prognosis prediction of non-small cell lung cancer (NSCLC). miRNA array was used to profile differentially express...

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Veröffentlicht in:	PloS one 2014-02, Vol.9 (2), p.e87780
Hauptverfasser:	Zhu, Wangyu, He, Jianying, Chen, Dongdong, Zhang, Bingjie, Xu, Liyun, Ma, Haijie, Liu, Xiaoguang, Zhang, Yongkui, Le, Hanbo
Format:	Artikel
Sprache:	eng
Schlagworte:	Aberration Adult Aged Analysis Area Under Curve Bioindicators Biology Biomarkers Biomarkers, Tumor - metabolism Cancer Cancer therapies Carcinogenesis Carcinogens Carcinoma, Non-Small-Cell Lung - genetics Carcinoma, Non-Small-Cell Lung - metabolism Case-Control Studies Cell cycle Cohort Studies Development and progression Embryos Female Gene Expression Profiling Gene Expression Regulation, Neoplastic Humans Laboratories Lung cancer Lung diseases Lung Neoplasms - genetics Lung Neoplasms - metabolism Male Medical diagnosis Medical prognosis Medicine Metastasis MicroRNA MicroRNAs MicroRNAs - genetics MicroRNAs - metabolism Middle Aged miRNA Non-small cell lung cancer Non-small cell lung carcinoma Patients Polymerase chain reaction Prognosis Prostate ROC Curve Serum levels Studies Surgery Thoracic surgery Tissues Tumors
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