Utility of 18F-FDG PET with a semi-quantitative index in the detection of sarcomatous transformation in patients with neurofibromatosis type 1

Malignant peripheral nerve sheath tumors (MPNSTs) are a serious complications of neurofibromatosis type 1 associated with poor prognosis and deeper lesions can be difficult to diagnose. 18-FDG PET improves the detection of malignancies. However, the criteria for malignancy, notably the SUVmax thresh...

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Veröffentlicht in:	PloS one 2014-02, Vol.9 (2), p.e85954
Hauptverfasser:	Combemale, Patrick, Valeyrie-Allanore, Laurence, Giammarile, Francesco, Pinson, Stephane, Guillot, Bernard, Goulart, Denis Mariano, Wolkenstein, Pierre, Blay, Jean Yves, Mognetti, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Benign Bioengineering Cancer Care and treatment Cell Transformation, Neoplastic - pathology Child Child, Preschool Complications Complications and side effects Demography Dermatology Female Fluorodeoxyglucose F18 Genetic disorders Hospitals Humans Imaging Lesions Life Sciences Likelihood ratio Liver Liver - diagnostic imaging Liver - pathology Liver Neoplasms - diagnostic imaging Liver Neoplasms - pathology Male Malignancy Medical diagnosis Medical imaging Medical research Medicine Middle Aged Neurofibromatosis Neurofibromatosis 1 - complications Neurofibromatosis 1 - diagnostic imaging Neurological disorders Neurons and Cognition NMR Nuclear magnetic resonance Nuclear medicine Pain Patients Positron emission Positron emission tomography Quantitative analysis Recklinghausen's disease Sarcoma Sarcoma - complications Sarcoma - diagnostic imaging Sarcoma - pathology Tomography Transformation Tumors
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