The role of matrix metalloproteinase in the intimal sarcoma-like cells derived from endarterectomized tissues from a chronic thromboembolic pulmonary hypertension patient

Sarcoma-like cells (SCLs) were derived from endarterectomized tissue of a single chronic thromboembolic pulmonary hypertension (CTEPH) patient during incubation of those thrombi at second passage as described at our previous report. These cells had malignant potential, with an increased expression o...

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Veröffentlicht in:	PloS one 2014-01, Vol.9 (1), p.e87489-e87489
Hauptverfasser:	Jujo, Takayuki, Sakao, Seiichiro, Tsukahara, Masanori, Kantake, Masashi, Kantake, Seiji, Maruoka, Miki, Tanabe, Nobuhiro, Masuda, Masahisa, Tatsumi, Koichiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Analysis Animal tissues Animals Arteries Biology Blotting, Western Cancer CD44 antigen Cell adhesion & migration Cell culture Cell Culture Techniques Embolisms Gelatinase A Growth factors Humans Hypertension Hypertension, Pulmonary - enzymology Hypertension, Pulmonary - metabolism Immunoglobulins Immunohistochemistry In vivo methods and tests Intermediate filament proteins Invasiveness Kinases Lung cancer Lungs Matrix metalloproteinase Matrix Metalloproteinase 14 - metabolism Matrix Metalloproteinase 14 - physiology Medicine Metalloproteinase Metastasis Mice Mice, SCID Neoplasm Invasiveness Pulmonary arteries Pulmonary artery Pulmonary Artery - pathology Pulmonary embolisms Pulmonary hypertension Sarcoma Sarcoma - pathology Thromboembolism Thrombosis Tumor Cells, Cultured Tumorigenesis Tumors Veins & arteries Vimentin Von Willebrand factor
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