Autophagy is involved in the cardioprotection effect of remote limb ischemic postconditioning on myocardial ischemia/reperfusion injury in normal mice, but not diabetic mice

Recent animal study and clinical trial data suggested that remote limb ischemic postconditioning (RIPostC) can invoke potent cardioprotection. However, during ischemia reperfusion injury (IR), the effect and mechanism of RIPostC on myocardium in subjects with or without diabetes mellitus (DM) are po...

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Veröffentlicht in:	PloS one 2014-01, Vol.9 (1), p.e86838-e86838
Hauptverfasser:	Han, Zhihua, Cao, Jiatian, Song, Dongqiang, Tian, Lei, Chen, Kan, Wang, Yue, Gao, Lin, Yin, Zhaofang, Fan, Yuqi, Wang, Changqian
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Autophagy Biology Blotting, Western Cardiology Cardiotonic Agents Cell death Clinical trials Diabetes Diabetes mellitus Diabetes Mellitus, Experimental - mortality Diabetes Mellitus, Experimental - pathology Disease Models, Animal Echocardiography Glucose Heart attacks Heart diseases Hindlimb - blood supply Hospitals Immunoenzyme Techniques Immunohistochemistry Injuries Ischemia Ischemic Preconditioning, Myocardial Kinases Laboratory animals Male Medical research Medical schools Medicine Mice Mice, Inbred C57BL Mortality Myocardial ischemia Myocardial Reperfusion Injury - mortality Myocardial Reperfusion Injury - pathology Myocardial Reperfusion Injury - prevention & control Myocardium Phagocytosis Proteins Reperfusion Rodents Streptozocin Survival Rate Veins & arteries Veterinary Science
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