Intensified tuberculosis case-finding in HIV-positive adults managed at Ethiopian health centers: diagnostic yield of Xpert MTB/RIF compared with smear microscopy and liquid culture

Detection of active tuberculosis (TB) before antiretroviral therapy (ART) initiation is important, but optimal diagnostic methods for use in resource-limited settings are lacking. We assessed the prevalence of TB, evaluated the diagnostic yield of Xpert MTB/RIF in comparison with smear microscopy an...

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Veröffentlicht in:	PloS one 2014-01, Vol.9 (1), p.e85478-e85478
Hauptverfasser:	Balcha, Taye T, Sturegård, Erik, Winqvist, Niclas, Skogmar, Sten, Reepalu, Anton, Jemal, Zelalem Habtamu, Tibesso, Gudeta, Schön, Thomas, Björkman, Per
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome Adult Adults AIDS Analysis Antibiotics Antibiotics, Antitubercular - pharmacology Antiretroviral agents Antiretroviral therapy Bacteriological Techniques - methods Basic Medicine Biology CD4 antigen Cell culture Clinical Medicine Demographics Diagnostic systems Disease control Drug resistance Drug Resistance, Bacterial Drug therapy Ethiopia - epidemiology Female Health facilities Highly active antiretroviral therapy HIV HIV Infections - complications HIV patients Human immunodeficiency virus Humans Immunosuppression Infections Infectious diseases Infectious Medicine Infektionsmedicin Klinisk medicin Liquid culture Lymph nodes Lymphadenopathy Male Mass Screening - methods Medical and Health Sciences Medical diagnosis Medical personnel MEDICIN Medicin och hälsovetenskap MEDICINE Medicinska och farmaceutiska grundvetenskaper Microbiology in the medical area Microscopy Microscopy - methods Mikrobiologi inom det medicinska området Molecular Diagnostic Techniques - methods Morning Mortality Mycobacterium tuberculosis Mycobacterium tuberculosis - drug effects Mycobacterium tuberculosis - genetics Nucleic Acid Amplification Techniques - methods Patients Prevalence Prospective Studies Public health Reproducibility of Results Rifampin - pharmacology RNA polymerase Sensitivity and Specificity Smear Sputum Sputum - microbiology Tuberculosis Tuberculosis - complications Tuberculosis - diagnosis Tuberculosis - epidemiology
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