Evidence from a mouse model that epithelial cell migration and mesenchymal-epithelial transition contribute to rapid restoration of uterine tissue integrity during menstruation

In women dynamic changes in uterine tissue architecture occur during each menstrual cycle. Menses, characterised by the shedding of the upper functional layer of the endometrium, is the culmination of a cascade of irreversible changes in tissue function including stromal decidualisation, inflammatio...

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Veröffentlicht in:	PloS one 2014-01, Vol.9 (1), p.e86378-e86378
Hauptverfasser:	Cousins, Fiona L, Murray, Alison, Esnal, Arantza, Gibson, Douglas A, Critchley, Hilary O D, Saunders, Philippa T K
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animal tissues Animals Architecture Biology Bleeding Breakdowns Bromodeoxyuridine Cell differentiation Cell migration Cell Movement Cell Proliferation Compartments Councils Culling Cytokeratin Endometrium Endometrium - cytology Endometrium - physiology Enzymes Epithelial cells Epithelial Cells - metabolism Epithelial-Mesenchymal Transition - genetics Estrous Cycle - genetics Female Gene expression Gene Expression Profiling Gene regulation Gene Regulatory Networks Genes Homeostasis Hormones House mouse Keratin Medical research Medicine Menstrual cycle Menstruation Mesenchyme Mice Models, Animal Molecular modelling Pregnancy Progesterone Progesterone - metabolism Reproductive health Restoration Shedding Stem cells Stromal Cells Studies Tissues Uterus Uterus - physiology Vagina
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