Expression variants of the lipogenic AGPAT6 gene affect diverse milk composition phenotypes in Bos taurus

Milk is composed of a complex mixture of lipids, proteins, carbohydrates and various vitamins and minerals as a source of nutrition for young mammals. The composition of milk varies between individuals, with lipid composition in particular being highly heritable. Recent reports have highlighted a re...

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Veröffentlicht in:	PloS one 2014-01, Vol.9 (1), p.e85757-e85757
Hauptverfasser:	Littlejohn, Mathew D, Tiplady, Kathryn, Lopdell, Thomas, Law, Tania A, Scott, Andrew, Harland, Chad, Sherlock, Ric, Henty, Kristen, Obolonkin, Vlad, Lehnert, Klaus, Macgibbon, Alistair, Spelman, Richard J, Davis, Stephen R, Snell, Russell G
Format:	Artikel
Sprache:	eng
Schlagworte:	Agriculture Analysis Animal lactation Animals Association analysis Base Sequence Bayesian analysis Biology Bos taurus Breeding of animals Carbohydrates Cattle Cattle - genetics Chromosomes Chromosomes, Mammalian - genetics Crosses, Genetic Dairy cattle Exons Fatty acids Female Gene expression Gene mapping Genes Genetic aspects Genetic Variation Genetics Genome-Wide Association Study Genomes Genomics Genotype Genotyping Glycerol-3-Phosphate O-Acyltransferase - genetics Lactation - genetics Lactose Lipid composition Lipids Lipids - genetics Lipogenesis - genetics Livestock Loci Male Mammary Glands, Animal - metabolism Mapping Milk Milk - metabolism Minerals Molecular Sequence Data Nucleotide sequence Nutrition Oils & fats Parameter estimation Pedigree Phenotype Phenotypes Populations Proteins Quantitative genetics Quantitative trait loci Quantitative Trait Loci - genetics R&D Research & development Ribonucleic acid RNA RNA, Messenger - genetics RNA, Messenger - metabolism Transcription Vitamins Yield
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