Factors affecting de novo urinary retention after Holmium laser enucleation of the prostate

Patients can experience urinary retention (UR) after Holmium laser enucleation of the prostate (HoLEP) that requires bladder distension during the procedure. The aim of this retrospective study is to identify factors affecting the UR after HoLEP. 336 patients, which underwent HoLEP for a symptomatic...

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Veröffentlicht in:PloS one 2014-01, Vol.9 (1), p.e84938-e84938
Hauptverfasser: Kim, Sung Han, Yoo, Changwon, Choo, Minsoo, Paick, Jae-Seung, Oh, Seung-June
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description Patients can experience urinary retention (UR) after Holmium laser enucleation of the prostate (HoLEP) that requires bladder distension during the procedure. The aim of this retrospective study is to identify factors affecting the UR after HoLEP. 336 patients, which underwent HoLEP for a symptomatic benign prostatic hyperplasia between July 2008 and March 2012, were included in this study. Urethral catheters were routinely removed one or two days after surgery. UR was defined as the need for an indwelling catheter placement following a failure to void after catheter removal. Demographic and clinical parameters were compared between the UR (n = 37) and the non-urinary retention (non-UR; n = 299) groups. The mean age of patients was 68.3 (±6.5) years and the mean operative time was 75.3 (±37.4) min. Thirty seven patients (11.0%) experienced a postoperative UR. UR patients voided catheter free an average of 1.9 (±1.7) days after UR. With regard to the causes of UR, 24 (7.1%) and 13 (3.9%) patients experienced a blood clot-related UR and a non-clot related UR respectively. Using multivariate analysis (p0.05). De novo UR after HoLEP was found to be self-limited and it was not related to learning curve, patient age, diabetes, or operative time. Efficient morcellation and careful control of bleeding, which reduces clot formation, decrease the risk of UR after HoLEP.
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The aim of this retrospective study is to identify factors affecting the UR after HoLEP. 336 patients, which underwent HoLEP for a symptomatic benign prostatic hyperplasia between July 2008 and March 2012, were included in this study. Urethral catheters were routinely removed one or two days after surgery. UR was defined as the need for an indwelling catheter placement following a failure to void after catheter removal. Demographic and clinical parameters were compared between the UR (n = 37) and the non-urinary retention (non-UR; n = 299) groups. The mean age of patients was 68.3 (±6.5) years and the mean operative time was 75.3 (±37.4) min. Thirty seven patients (11.0%) experienced a postoperative UR. UR patients voided catheter free an average of 1.9 (±1.7) days after UR. With regard to the causes of UR, 24 (7.1%) and 13 (3.9%) patients experienced a blood clot-related UR and a non-clot related UR respectively. Using multivariate analysis (p&lt;0.05), we found significant differences between the UR and the non-UR groups with regard to a morcellation efficiency (OR 0.701, 95% CI 0.498-0.988) and a bleeding-related complication, such as, a reoperation for bleeding (OR 0.039, 95% CI 0.004-0.383) or a transfusion (OR 0.144, 95% CI 0.027-0.877). Age, history of diabetes, prostate volume, pre-operative post-void residual, bladder contractility index, learning curve, and operative time were not significantly associated with the UR (p&gt;0.05). De novo UR after HoLEP was found to be self-limited and it was not related to learning curve, patient age, diabetes, or operative time. Efficient morcellation and careful control of bleeding, which reduces clot formation, decrease the risk of UR after HoLEP.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0084938</identifier><identifier>PMID: 24465454</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Age ; Age Factors ; Aged ; Bladder ; Bleeding ; Blood coagulation ; Catheters ; Comparative analysis ; Contractility ; Demographics ; Diabetes Complications ; Diabetes mellitus ; Diabetes Mellitus - pathology ; Diabetes Mellitus - surgery ; Distension ; Enucleation ; Holmium ; Hospitals ; Humans ; Hyperplasia ; Identification methods ; Intubation ; Laser surgery ; Lasers ; Learning Curve ; Male ; Mathematics ; Medical instruments ; Medical records ; Medical research ; Medicine ; Middle Aged ; Multivariate analysis ; Operative Time ; Patients ; Postoperative Hemorrhage - prevention &amp; control ; Prostate ; Prostate - pathology ; Prostate - surgery ; Prostate cancer ; Prostatic Hyperplasia - complications ; Prostatic Hyperplasia - pathology ; Prostatic Hyperplasia - surgery ; Rare earth metal compounds ; Retention ; Risk reduction ; Statistical analysis ; Surgery ; Transfusion ; Transurethral Resection of Prostate - adverse effects ; Transurethral Resection of Prostate - methods ; Urinary bladder ; Urinary Catheterization ; Urinary Retention - etiology ; Urinary Retention - prevention &amp; control ; Urine ; Urogenital system ; Urology</subject><ispartof>PloS one, 2014-01, Vol.9 (1), p.e84938-e84938</ispartof><rights>COPYRIGHT 2014 Public Library of Science</rights><rights>2014 Kim et al. 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The aim of this retrospective study is to identify factors affecting the UR after HoLEP. 336 patients, which underwent HoLEP for a symptomatic benign prostatic hyperplasia between July 2008 and March 2012, were included in this study. Urethral catheters were routinely removed one or two days after surgery. UR was defined as the need for an indwelling catheter placement following a failure to void after catheter removal. Demographic and clinical parameters were compared between the UR (n = 37) and the non-urinary retention (non-UR; n = 299) groups. The mean age of patients was 68.3 (±6.5) years and the mean operative time was 75.3 (±37.4) min. Thirty seven patients (11.0%) experienced a postoperative UR. UR patients voided catheter free an average of 1.9 (±1.7) days after UR. With regard to the causes of UR, 24 (7.1%) and 13 (3.9%) patients experienced a blood clot-related UR and a non-clot related UR respectively. Using multivariate analysis (p&lt;0.05), we found significant differences between the UR and the non-UR groups with regard to a morcellation efficiency (OR 0.701, 95% CI 0.498-0.988) and a bleeding-related complication, such as, a reoperation for bleeding (OR 0.039, 95% CI 0.004-0.383) or a transfusion (OR 0.144, 95% CI 0.027-0.877). Age, history of diabetes, prostate volume, pre-operative post-void residual, bladder contractility index, learning curve, and operative time were not significantly associated with the UR (p&gt;0.05). De novo UR after HoLEP was found to be self-limited and it was not related to learning curve, patient age, diabetes, or operative time. Efficient morcellation and careful control of bleeding, which reduces clot formation, decrease the risk of UR after HoLEP.</description><subject>Age</subject><subject>Age Factors</subject><subject>Aged</subject><subject>Bladder</subject><subject>Bleeding</subject><subject>Blood coagulation</subject><subject>Catheters</subject><subject>Comparative analysis</subject><subject>Contractility</subject><subject>Demographics</subject><subject>Diabetes Complications</subject><subject>Diabetes mellitus</subject><subject>Diabetes Mellitus - pathology</subject><subject>Diabetes Mellitus - surgery</subject><subject>Distension</subject><subject>Enucleation</subject><subject>Holmium</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Hyperplasia</subject><subject>Identification methods</subject><subject>Intubation</subject><subject>Laser surgery</subject><subject>Lasers</subject><subject>Learning Curve</subject><subject>Male</subject><subject>Mathematics</subject><subject>Medical instruments</subject><subject>Medical records</subject><subject>Medical research</subject><subject>Medicine</subject><subject>Middle Aged</subject><subject>Multivariate analysis</subject><subject>Operative Time</subject><subject>Patients</subject><subject>Postoperative Hemorrhage - prevention &amp; control</subject><subject>Prostate</subject><subject>Prostate - pathology</subject><subject>Prostate - surgery</subject><subject>Prostate cancer</subject><subject>Prostatic Hyperplasia - complications</subject><subject>Prostatic Hyperplasia - pathology</subject><subject>Prostatic Hyperplasia - surgery</subject><subject>Rare earth metal compounds</subject><subject>Retention</subject><subject>Risk reduction</subject><subject>Statistical analysis</subject><subject>Surgery</subject><subject>Transfusion</subject><subject>Transurethral Resection of Prostate - adverse effects</subject><subject>Transurethral Resection of Prostate - methods</subject><subject>Urinary bladder</subject><subject>Urinary Catheterization</subject><subject>Urinary Retention - etiology</subject><subject>Urinary Retention - prevention &amp; control</subject><subject>Urine</subject><subject>Urogenital system</subject><subject>Urology</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>DOA</sourceid><recordid>eNqNk11r2zAUhs3YWLts_2BshsHYLpJZH5alm0Ep6xooFPZ1swshy8eJgi1lklzWf18lcUs8ejEM_pCe99U5x-dk2WtULBCp0KeNG7xV3WLrLCyKglNB-JPsFAmC5wwX5OnR-0n2IoRNUZSEM_Y8O8GUspKW9DT7faF0dD7kqm1BR2NXeQO5dTcuH7yxyt_mHiLYaJxNTASfX7quN0OfdyqkL7CD7kDt912bxzXkW-9CVBFeZs9a1QV4NT5n2c-LLz_OL-dX11-X52dXc80EjnNdUkQEQgVloqkVajDhWhNCynRXUBWIVVpoBLWmhS4ZQhpT3rC2xppBrcgse3vw3XYuyLEuQSIqCiEwxSwRywPROLWRW2_6lJh0ysj9gvMrqXw0KZGkoooLXmslFCVNKwQhQGtSlhQQSZHOss_jaUPdQ6NTbbzqJqbTHWvWcuVuJOGiIpwkgw-jgXd_BghR9iZo6DplwQ37uDHjvKI4oe_-QR_PbqRWKiVgbOvSuXpnKs9oxXkKvdpRi0eodDXQG52aqDVpfSL4OBEkJsLfuFJDCHL5_dv_s9e_puz7I3YNqovr4Lph10JhCtIDqFNDBQ_tQ5FRIXczcF8NuZsBOc5Akr05_kEPovumJ3dRbAG6</recordid><startdate>20140121</startdate><enddate>20140121</enddate><creator>Kim, Sung Han</creator><creator>Yoo, Changwon</creator><creator>Choo, Minsoo</creator><creator>Paick, Jae-Seung</creator><creator>Oh, Seung-June</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20140121</creationdate><title>Factors affecting de novo urinary retention after Holmium laser enucleation of the prostate</title><author>Kim, Sung Han ; 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The aim of this retrospective study is to identify factors affecting the UR after HoLEP. 336 patients, which underwent HoLEP for a symptomatic benign prostatic hyperplasia between July 2008 and March 2012, were included in this study. Urethral catheters were routinely removed one or two days after surgery. UR was defined as the need for an indwelling catheter placement following a failure to void after catheter removal. Demographic and clinical parameters were compared between the UR (n = 37) and the non-urinary retention (non-UR; n = 299) groups. The mean age of patients was 68.3 (±6.5) years and the mean operative time was 75.3 (±37.4) min. Thirty seven patients (11.0%) experienced a postoperative UR. UR patients voided catheter free an average of 1.9 (±1.7) days after UR. With regard to the causes of UR, 24 (7.1%) and 13 (3.9%) patients experienced a blood clot-related UR and a non-clot related UR respectively. Using multivariate analysis (p&lt;0.05), we found significant differences between the UR and the non-UR groups with regard to a morcellation efficiency (OR 0.701, 95% CI 0.498-0.988) and a bleeding-related complication, such as, a reoperation for bleeding (OR 0.039, 95% CI 0.004-0.383) or a transfusion (OR 0.144, 95% CI 0.027-0.877). Age, history of diabetes, prostate volume, pre-operative post-void residual, bladder contractility index, learning curve, and operative time were not significantly associated with the UR (p&gt;0.05). De novo UR after HoLEP was found to be self-limited and it was not related to learning curve, patient age, diabetes, or operative time. Efficient morcellation and careful control of bleeding, which reduces clot formation, decrease the risk of UR after HoLEP.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>24465454</pmid><doi>10.1371/journal.pone.0084938</doi><tpages>e84938</tpages><oa>free_for_read</oa></addata></record>
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subjects Age
Age Factors
Aged
Bladder
Bleeding
Blood coagulation
Catheters
Comparative analysis
Contractility
Demographics
Diabetes Complications
Diabetes mellitus
Diabetes Mellitus - pathology
Diabetes Mellitus - surgery
Distension
Enucleation
Holmium
Hospitals
Humans
Hyperplasia
Identification methods
Intubation
Laser surgery
Lasers
Learning Curve
Male
Mathematics
Medical instruments
Medical records
Medical research
Medicine
Middle Aged
Multivariate analysis
Operative Time
Patients
Postoperative Hemorrhage - prevention & control
Prostate
Prostate - pathology
Prostate - surgery
Prostate cancer
Prostatic Hyperplasia - complications
Prostatic Hyperplasia - pathology
Prostatic Hyperplasia - surgery
Rare earth metal compounds
Retention
Risk reduction
Statistical analysis
Surgery
Transfusion
Transurethral Resection of Prostate - adverse effects
Transurethral Resection of Prostate - methods
Urinary bladder
Urinary Catheterization
Urinary Retention - etiology
Urinary Retention - prevention & control
Urine
Urogenital system
Urology
title Factors affecting de novo urinary retention after Holmium laser enucleation of the prostate
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