Atheroprotective effect of oleoylethanolamide (OEA) targeting oxidized LDL

Dietary fat-derived lipid oleoylethanolamide (OEA) has shown to modulate lipid metabolism through a peroxisome proliferator-activated receptor-alpha (PPAR-α)-mediated mechanism. In our study, we further demonstrated that OEA, as an atheroprotective agent, modulated the atherosclerotic plaques develo...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2014-01, Vol.9 (1), p.e85337
Hauptverfasser:	Fan, Angran, Wu, Xiaofeng, Wu, Huijuan, Li, Long, Huang, Rui, Zhu, Yueyong, Qiu, Yan, Fu, Jin, Ren, Jie, Zhu, Chenggang
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal tissues Animals Aorta Apolipoprotein E Apoptosis Apoptosis - drug effects Arteriosclerosis Atherosclerosis Atherosclerosis - drug therapy Biology Cardiovascular disease Carotid arteries Catheters Cell cycle Cell Line Cell migration Cell Movement - drug effects Cell proliferation Cell Proliferation - drug effects Cells, Cultured Cholesterol Coronary vessels Cyclooxygenase-2 Denudation Diet Dietary fat Endocannabinoids Endothelial cells Fatty acids Gene expression Heart Humans In vivo methods and tests Inflammation Interleukin 6 Laboratory animals Ligands Lipid metabolism Lipids Lipopolysaccharides Lipoproteins (low density) Lipoproteins, LDL - metabolism Low density lipoprotein Low density lipoproteins Medicine Metabolism Mice Mitogens Muscles Nitric-oxide synthase Oils & fats Oleic acid Oleic Acids - therapeutic use Oxidation Peroxisome proliferator-activated receptors Pharmacology Plaques PPAR alpha - metabolism Rats Real-Time Polymerase Chain Reaction RNA Rodents Science Smooth muscle Tumor necrosis factor-α Vascular system
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!